4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans-

Base Information

• Chemical Name: 4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans-
• CAS No.: 23349-82-8
• Molecular Formula: C5H10N2O3
• Molecular Weight: 146.14400
• European Community (EC) Number: 607-221-7
• UNII: 23HU0A2VUH
• Wikidata: Q27253754
• Mol file: 23349-82-8.mol

Synonyms:23HU0A2VUH;4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans-;UNII-23HU0A2VUH;23349-82-8;2-Imidazolidinone, 4,5-dihydroxy-1,3-dimethyl-, trans-;2-Imidazolidinone, 4,5-dihydroxy-1,3-dimethyl-, (4R,5R)-rel-;SCHEMBL10746679;trans-4,5-dihydroxy-1,3-dimethylimidazolidin-2-one;Q27253754

Chemical Property of 4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans-

Chemical Property:

• Vapor Pressure: 0.000108mmHg at 25°C
• PSA: 64.01000
• LogP: -1.50380
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 146.06914219
• Heavy Atom Count: 10
• Complexity: 145

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1C(C(N(C1=O)C)O)O
• Isomeric SMILES: CN1[C@@H]([C@H](N(C1=O)C)O)O

Technology Process of 4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans-

There total 8 articles about 4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1,1-Dimethylurea (598-94-7) → 4,5-dihydroxy-1,3-dimethylimidazolidin-2-one (3923-79-3,23349-82-8)

Guidance literature:

In methanol;

Reference yield: 38.0%

Glyoxal (131543-46-9,107-22-2) + N,N'-Dimethylurea (96-31-1) → (4S,5R)-4,5-Dihydroxy-1,3-dimethyl-imidazolidin-2-one + trans-1,3-dimethyl-4,5-dihydroxyimidazolidin-2-one (23349-82-8)

Guidance literature:

With sodium hydroxide; water; at 20 ℃; for 5h; pH=8 - 9;

Reference yield: 32.0%

N,N'-Dimethylurea (96-31-1) + glyoxal bis-hydrate (44307-07-5) → trans-1,3-dimethyl-4,5-dihydroxyimidazolidin-2-one (23349-82-8)

Guidance literature:

With hydrogenchloride; In water; at 45 - 50 ℃; for 2h; pH=4 - 4.5;

DOI:10.1002/jhet.5570430523

upstream raw materials:

1,1-Dimethylurea

Glyoxal

N,N'-Dimethylurea

glyoxal bis-hydrate

Downstream raw materials:

(E)-5-(benzylidene)-1,3-dimethylimidazolidine-2,4-dione

(Z)-5-(benzylidene)-1,3-dimethylimidazolidine-2,4-dione

(E)-5-(4-methoxybenzylidene)-1,3-dimethylimidazolidine-2,4-dione

(E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one