Phenol, 2-(3-phenyl-2-propenyl)-

Base Information

• Chemical Name: Phenol, 2-(3-phenyl-2-propenyl)-
• CAS No.: 24114-57-6
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Mol file: 24114-57-6.mol

Synonyms:

Chemical Property of Phenol, 2-(3-phenyl-2-propenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenol, 2-(3-phenyl-2-propenyl)-

There total 19 articles about Phenol, 2-(3-phenyl-2-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one (1214-47-7) → 3-(2-hydroxyphenyl)-1-phenyl-1-propene (24114-57-6)

Guidance literature:

1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one; With chloroformic acid ethyl ester; In tetrahydrofuran; at 0 ℃; for 2h;

With sodium tetrahydroborate; In tetrahydrofuran; water; at 0 ℃; for 12h;

DOI:10.1021/jacs.8b02607

Reference yield: 60.0%

phenyl 3-phenyl-allyl ether (37464-41-8,16519-25-8) + 2-hydroxyphenyl boronic acid (89466-08-0) → 3-(2-hydroxyphenyl)-1-phenyl-1-propene (24114-57-6)

Guidance literature:

With C₂₂H₄₆N₄; palladium diacetate; calcium hydroxide; In N,N-dimethyl acetamide; water; at 20 - 80 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.201201276

Reference yield: 57.0%

cinnamyl chloride (2687-12-9) + phenol (108-95-2,27073-41-2) → 3-(2-hydroxyphenyl)-1-phenyl-1-propene (24114-57-6)

Guidance literature:

phenol; With sodium hydride; In diethyl ether; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

cinnamyl chloride; In diethyl ether; mineral oil; at 37 ℃; for 6h; Inert atmosphere;

DOI:10.1021/acs.orglett.9b01258

upstream raw materials:

sodium phenoxide

Cinnamyl bromide

benzene

phenol

Downstream raw materials:

2-(3-phenylpropyl)phenol

flavan

(1R,2R)-3-(2-hydroxyphenyl)-1-phenylpropane-1,2-diol

C₁₇H₂₀O₄