3-Hydroxy-4-Methylquinolin-2(1H)-one

Base Information

• Chemical Name: 3-Hydroxy-4-Methylquinolin-2(1H)-one
• CAS No.: 24186-98-9
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.18400
• Hs Code.: 2933790090
• Mol file: 24186-98-9.mol

Synonyms:4-methyl-3-hydroxy-2-quinolone;3-hydroxyquinolin-2(1H)-one,23;3-Hydroxy-4-methyl-carbostyril;3-hydroxy-4-methyl-2-quinolone;4-methyl-3-hydroxyquinolin-2(1H)-one;3-hydroxy-4-methylquinolin-2(1H)-one;2(1H)-Quinolinone,3-hydroxy-4-methyl;

Chemical Property of 3-Hydroxy-4-Methylquinolin-2(1H)-one

Chemical Property:

• PSA: 53.35000
• LogP: 1.95440

Purity/Quality:

99% ^*data from raw suppliers

3-Hydroxy-4-methylquinolin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Hydroxy-4-Methylquinolin-2(1H)-one

There total 14 articles about 3-Hydroxy-4-Methylquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

Trimethylboroxine (823-96-1) + 4-bromo-3-hydroxyquinolin-2(1H)-one (176170-14-2) → 3-hydroxy-4-methylquinolin-2(1H)-one (24186-98-9)

Guidance literature:

4-bromo-3-hydroxyquinolin-2(1H)-one; With chloro-trimethyl-silane; triethylamine; In toluene; at 20 ℃; for 4h;

Trimethylboroxine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; water; for 10h; Inert atmosphere; Reflux;

Reference yield: 36.0%

Trimethylboroxine (823-96-1) + C12H15NO2Si → 3-hydroxy-4-methylquinolin-2(1H)-one (24186-98-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; water; for 10h; Inert atmosphere; Reflux;

DOI:10.1021/ml4001112

Reference yield: 20.0%

Diazoethan (1117-96-0) + indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → 3-hydroxy-4-methylquinolin-2(1H)-one (24186-98-9)

Guidance literature:

In methanol; diethyl ether; Ambient temperature;

upstream raw materials:

N-(2-acetylphenyl)-2-chloroacetamide

C₆H₄NCH₂CHCCH₂

water

dihydrogen peroxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 24186-98-9 3-Hydroxy-4-Methylquinolin-2(1H)-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send