2,3,5,6-Tetrafluoropyridine

Base Information

Chemical Name:2,3,5,6-Tetrafluoropyridine
CAS No.:2875-18-5
Molecular Formula:C5HF4N
Molecular Weight:151.063
Hs Code.:29333990
European Community (EC) Number:622-979-9
DSSTox Substance ID:DTXSID40182930
Nikkaji Number:J100.016K
Wikidata:Q72505249
Mol file:2875-18-5.mol

Synonyms:Pyridine,2,3,5,6-tetrafluoro-

Suppliers and Price of 2,3,5,6-Tetrafluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2,3,5,6-Tetrafluoropyridine
10g
$ 171.00

Alfa Aesar
2,3,5,6-Tetrafluoropyridine, 97%
1g
$ 41.10

Alfa Aesar
2,3,5,6-Tetrafluoropyridine, 97%
5g
$ 140.00

Ambeed
2,3,5,6-Tetrafluoropyridine 97%
25g
$ 132.00

Ambeed
2,3,5,6-Tetrafluoropyridine 97%
10g
$ 54.00

Ambeed
2,3,5,6-Tetrafluoropyridine 97%
1g
$ 12.00

Ambeed
2,3,5,6-Tetrafluoropyridine 97%
5g
$ 38.00

American Custom Chemicals Corporation
2,3,5,6-TETRAFLUOROPYRIDINE 95.00%
1G
$ 606.38

American Custom Chemicals Corporation
2,3,5,6-TETRAFLUOROPYRIDINE 95.00%
5G
$ 860.48

American Custom Chemicals Corporation
2,3,5,6-TETRAFLUOROPYRIDINE 95.00%
25G
$ 1380.23

Total 122 raw suppliers

Chemical Property of 2,3,5,6-Tetrafluoropyridine

Chemical Property:

Appearance/Colour:clear colorless liquid
Vapor Pressure:42.2mmHg at 25°C
Refractive Index:n20/D 1.4046(lit.)
Boiling Point:106 °C at 760 mmHg
PKA:-10.94±0.20(Predicted)
Flash Point:30.6 °C
PSA：12.89000
Density:1.518 g/cm³
LogP:1.63800
Storage Temp.:Refrigerator
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:151.00451168
Heavy Atom Count:10
Complexity:108

Purity/Quality:

98% ^*data from raw suppliers

2,3,5,6-Tetrafluoropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, F, C
Hazard Codes:Xi,F,C
Statements: 10-36/37/38
Safety Statements: 28-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(C(=NC(=C1F)F)F)F
Description Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medicine, pesticides, rubber, dyes and other fields. Since the 1960s, there have been hundreds of medicines, pesticides, dyes, and some special reagents developed with fluorine-containing aromatic compounds as intermediates. In the weakly basic pyridine ring, the nitrogen atom is more negatively charged, and then a fluorine atom with a strong electronegativity is introduced to synthesize a fluorine-containing pyridine intermediate.

Technology Process of 2,3,5,6-Tetrafluoropyridine

There total 23 articles about 2,3,5,6-Tetrafluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 617-86-7
triethylsilane

: 700-16-3
Pentafluoropyridine

: 2875-18-5
2,3,5,6-tetrafluoropyridine

: 358-43-0
triethylsilyl fluoride

Guidance literature:: With dmap; (1,3-bis(2,4,6-trimethylphenyl)imidazolin-2-ylidene)AuH; In dichloromethane; at 40 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ja305204y

Reference yield: 73.0%

: 700-16-3
Pentafluoropyridine

: 3512-13-8,63745-12-0
2,3,4,6-tetrafluoropyridine

: 2875-18-5
2,3,5,6-tetrafluoropyridine

Guidance literature:: With C₃₂H₄₆N₂Ru; sodium carbonate; isopropyl alcohol; at 70 ℃; for 24h; Inert atmosphere; Schlenk technique; Glovebox;
DOI:10.1021/acscatal.6b02004

Reference yield: 70.0%

: 621-23-8
1,2,3-trimethoxybenzene

: 700-16-3
Pentafluoropyridine

: 2875-18-5
2,3,5,6-tetrafluoropyridine

: 2,3,5,6-tetrafluoro-4-(2,4,6-trimethoxyphenyl)pyridine

Guidance literature:: With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); potassium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 0 ℃; for 24h; Reagent/catalyst; Solvent; Time; Temperature; regioselective reaction; Catalytic behavior; Inert atmosphere; Photolysis;
DOI:10.1021/jacs.5b13450