N-(1-hydroxypropan-2-yl)benzamide

Base Information

Chemical Name:N-(1-hydroxypropan-2-yl)benzamide
CAS No.:24629-34-3
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:2924299090
DSSTox Substance ID:DTXSID70409066
Mol file:24629-34-3.mol

Synonyms:N-(1-hydroxypropan-2-yl)benzamide;24629-34-3;Benzamide, N-(2-hydroxy-1-methylethyl)-;N-(2-hydroxy-1-methylethyl)benzamide;SCHEMBL3380039;DTXSID70409066;AMY10526;AKOS005766749;SB84305;FT-0731044;L10159

Suppliers and Price of N-(1-hydroxypropan-2-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(1-Hydroxypropan-2-yl)benzamide 95+%
5g
$ 831.00

American Custom Chemicals Corporation
BENZAMIDE, N-(2-HYDROXY-1-METHYLETHYL)- 95.00%
5MG
$ 495.30

Alichem
N-(1-Hydroxypropan-2-yl)benzamide
1g
$ 237.44

Total 16 raw suppliers

Chemical Property of N-(1-hydroxypropan-2-yl)benzamide

Chemical Property:

Melting Point:102-103℃
PSA：52.82000
Density:1.115
LogP:1.37200
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:164

Purity/Quality:

98%min ^*data from raw suppliers

N-(1-Hydroxypropan-2-yl)benzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO)NC(=O)C1=CC=CC=C1

Technology Process of N-(1-hydroxypropan-2-yl)benzamide

There total 16 articles about N-(1-hydroxypropan-2-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 93-58-3,5705-52-2,80226-58-0
benzoic acid methyl ester

: 6168-72-5
2-Amino-1-propanol

: 24629-34-3
N-(1-hydroxypropan-2-yl)benzamide

Guidance literature:: With C₁₈H₁₅IMnN₃O₃; sodium t-butanolate; In toluene; at 60 ℃; for 18h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.0c02478

Reference yield: 85.0%

: 7244-67-9,38767-73-6
methyl N-benzoylalaninate

: 24629-34-3
N-(1-hydroxypropan-2-yl)benzamide

Guidance literature:: With sodium tetrahydroborate; calcium chloride; In tetrahydrofuran; methanol; at 0 ℃; for 12h;
DOI:10.1016/j.tet.2008.05.015

Reference yield:

: 78007-50-8
N-(prop-1-en-2-yl)benzamide

: 24629-34-3
N-(1-hydroxypropan-2-yl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline / tetrahydrofuran / 3 h / 80 °C / Inert atmosphere; Sealed tube

2: sodium perborate tetrahydrate / tetrahydrofuran; water / 6 h / 20 °C

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; sodium perborate tetrahydrate; (S)-2-<4,5-dihydro-4-(1,1-dimethylethyl)oxazol-2-yl>quinoline; In tetrahydrofuran; water;
DOI:10.1021/jacs.0c05213