Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate

Base Information

Chemical Name:Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate
CAS No.:247574-58-9
Molecular Formula:C11H12ClF3NO4P
Molecular Weight:345.643
Hs Code.:
DSSTox Substance ID:DTXSID201151117

Synonyms:Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate;SCHEMBL12621318;MTURQALKJIEXHW-KUSNVBIKSA-N;DTXSID201151117;247574-58-9;N-[Chloro[4-(trifluoromethyl)phenoxy]phosphinyl]-L-alanine methyl ester

Suppliers and Price of Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:345.0144570
Heavy Atom Count:21
Complexity:413

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)OC)NP(=O)(OC1=CC=C(C=C1)C(F)(F)F)Cl
Isomeric SMILES:C[C@@H](C(=O)OC)NP(=O)(OC1=CC=C(C=C1)C(F)(F)F)Cl

Technology Process of Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate

There total 4 articles about Methyl (2S)-2-[[chloro-[4-(trifluoromethyl)phenoxy]phosphoryl]amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 247574-58-9
4-(trifluoromethyl)-phenyl-(methoxy-L-alaninyl)-phosphorochloridate

Guidance literature:

Reference yield:

: 840506-68-5
4-(trifluoromethyl)-phenyl-phosphodichloridate

: 67436-20-8
p-toluenesulfonic acid salt of (S)-α-alanine

: 247574-58-9
4-(trifluoromethyl)-phenyl-(methoxy-L-alaninyl)-phosphorochloridate

Guidance literature:: With triethylamine; In dichloromethane; at -78 - 20 ℃;
DOI:10.1021/jm060776w

Reference yield:

: 402-45-9
4-hydroxybenzotrifluoride

: 247574-58-9
4-(trifluoromethyl)-phenyl-(methoxy-L-alaninyl)-phosphorochloridate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; phosphorus oxychloride / diethyl ether; tetrahydrofuran / -78 - 20 °C

2: triethylamine / CH₂Cl₂ / -78 - 20 °C

With triethylamine; trichlorophosphate; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jm060776w