1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-

Base Information

Chemical Name:1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-
CAS No.:247587-56-0
Molecular Formula:C20H44O6SSi2
Molecular Weight:468.803
Hs Code.:

1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-

Synonyms:

Suppliers and Price of 1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)-

There total 6 articles about 1,3-Cyclohexanediol,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, 3-methanesulfonate, (1S,3R,4R,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 247587-55-9
(1R,2S,3S,5S)-5-benzyloxy-3-(tert-butyldimethylsilyloxy)-2-(tert-butyldimethylsilyloxymethyl)-1-methanesulfonyloxycyclohexane

: 247587-56-0
(1R,3R,4R,5S)-4-tert-butyldimethylsilyloxymethyl-5-tert-butyldimethylsilyloxy-3-methanesulfonyloxycyclohexanol

Guidance literature:: With ammonium formate; palladium on activated charcoal; for 14h; Heating;
DOI:10.1021/jo9908288

Reference yield:

: 247587-54-8
(1R,2S,3S,5S)-5-benzyloxy-3-(tert-butyldimethylsilyloxy)-2-(tert-butyldimethylsilyloxymethyl)cyclohexanol

: 247587-56-0
(1R,3R,4R,5S)-4-tert-butyldimethylsilyloxymethyl-5-tert-butyldimethylsilyloxy-3-methanesulfonyloxycyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Et₃N / CH₂Cl₂

2: 76 percent / HCOONH₄ / Pd/C / methanol

With ammonium formate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1081/NCN-100002360

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 247587-56-0
(1R,3R,4R,5S)-4-tert-butyldimethylsilyloxymethyl-5-tert-butyldimethylsilyloxy-3-methanesulfonyloxycyclohexanol

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / imidazole / dimethylformamide / 20 °C

2: 92 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

3: 97 percent / HCOONH₄ / Pd/C / 14 h / Heating

With 1H-imidazole; ammonium formate; triethylamine; palladium on activated charcoal; In dichloromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Substitution / 3: Hydrogenolysis;
DOI:10.1021/jo9908288