4-Isoxazolecarboxylic acid, 3,5-diphenyl-

Base Information

Chemical Name:4-Isoxazolecarboxylic acid, 3,5-diphenyl-
CAS No.:2505-98-8
Molecular Formula:C16H11NO3
Molecular Weight:265.268
Hs Code.:
Mol file:2505-98-8.mol

Synonyms:

Suppliers and Price of 4-Isoxazolecarboxylic acid, 3,5-diphenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of 4-Isoxazolecarboxylic acid, 3,5-diphenyl-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Isoxazolecarboxylic acid, 3,5-diphenyl-

There total 21 articles about 4-Isoxazolecarboxylic acid, 3,5-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2289-55-6
methyl [3,5-diphenylisoxazol-4-yl]carboxylate

: 2505-98-8
3,5-diphenyl-isoxazole-4-carboxylic acid

Guidance literature:: methyl [3,5-diphenylisoxazol-4-yl]carboxylate; With potassium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 16h;

With hydrogenchloride; In water; pH=< 5;
DOI:10.1021/jm301905a

Reference yield: 80.0%

: 873-67-6
benzonitrile oxide

: 637-44-5
phenylpropyolic acid

: 2505-98-8
3,5-diphenyl-isoxazole-4-carboxylic acid

Guidance literature:: With 2-nitrophenylboronic acid; In 1,2-dichloro-ethane; at 25 ℃; for 24h; regioselective reaction; Inert atmosphere;
DOI:10.1002/chem.200903484

Reference yield:

: 698-16-8
benzohydroximoyl chloride

: 2505-98-8
3,5-diphenyl-isoxazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 0 °C

2: 2.) tetra-n-butylammonium hydroxide / 1.) THF, rt, 40 h;

With tetra(n-butyl)ammonium hydroxide; triethylamine; In tetrahydrofuran;