Chemical Property of Phenylpropiolic acid
Chemical Property:
- Appearance/Colour:Slightly beige crystalline powder.
- Vapor Pressure:0.000433mmHg at 25°C
- Melting Point:135-137 °C(lit.)
- Refractive Index:1.5550 (estimate)
- Boiling Point:302.6 °C at 760 mmHg
- PKA:pK1:2.269 (35°C)
- Flash Point:151 °C
- PSA：37.30000
- Density:1.24 g/cm3
- LogP:1.12270
- Storage Temp.:0-6°C
- Water Solubility.:freely soluble
- XLogP3:2
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:1
- Exact Mass:146.036779430
- Heavy Atom Count:11
- Complexity:200
- Purity/Quality:
-
99% *data from raw suppliers
Phenylpropiolic acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC=C(C=C1)C#CC(=O)O
-
Uses
Phenylpropiolic Acid is used as a reagent in the high yield synthesis of 3,3-diphenylpropanoic acid derivatives via hydrophenylation and ionic hydrogenation with strong Lewis acids. It is also used in the synthesis of highly substituted aromatic rings via the alkyne-mediated approach which serve as templates for drug design.
