4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Base Information

Chemical Name:4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide
CAS No.:251992-92-4
Molecular Formula:C14H9BrN2OS2
Molecular Weight:365.274
Hs Code.:
DSSTox Substance ID:DTXSID60433214
Nikkaji Number:J1.525.123I
Wikidata:Q82247343
Pharos Ligand ID:3K8XVNL56CKB
ChEMBL ID:CHEMBL266198
Mol file:251992-92-4.mol

Synonyms:CHEMBL266198;251992-92-4;4-[(4-bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide;SCHEMBL7056150;DTXSID60433214;4-(4-bromophenyl)sulfanylthieno[2,3-c]pyridine-2-carboxamide;BDBM50098480;4-(4-Bromo-phenylsulfanyl)-thieno[2,3-c]pyridine-2-carboxylic acid amide

Suppliers and Price of 4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:363.93397
Heavy Atom Count:20
Complexity:363

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1SC2=C3C=C(SC3=CN=C2)C(=O)N)Br

Technology Process of 4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

There total 8 articles about 4-[(4-Bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 402582-08-5
methyl 4-[(4-bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxylate

: 251992-92-4
4-[(4-bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Guidance literature:: With ammonia; In methanol; at 45 ℃; for 18h;
DOI:10.1021/jo016171j

Reference yield:

: 4-(4-bromo-phenylsulfanyl)-thieno[2,3-c]pyridine-2-carbonyl chloride

: 251992-92-4
4-[(4-bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Guidance literature:: With ammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1021/jm000452m

Reference yield:

: 136590-83-5
3,5-dichloropyridine-4-carboxaldehyde

: 251992-92-4
4-[(4-bromophenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / dimethylformamide / 4 h / 0 - 20 °C

2: 432 mg / K₂CO₃ / dimethylformamide / 2.5 h / 20 - 70 °C

3: 95 percent / NH₃ / methanol / 18 h / 45 °C

With ammonia; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo016171j