1-Iodo-8-phenylnaphthalene

Base Information

• Chemical Name: 1-Iodo-8-phenylnaphthalene
• CAS No.: 25308-69-4
• Molecular Formula: C16H11I
• Molecular Weight: 330.168
• DSSTox Substance ID: DTXSID80552077
• Wikidata: Q82432066
• Mol file: 25308-69-4.mol

Synonyms:1-Iodo-8-phenylnaphthalene;25308-69-4;SCHEMBL18786372;DTXSID80552077

Chemical Property of 1-Iodo-8-phenylnaphthalene

Chemical Property:

• PSA: 0.00000
• LogP: 5.11140
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 329.99055
• Heavy Atom Count: 17
• Complexity: 244

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC3=C2C(=CC=C3)I

Technology Process of 1-Iodo-8-phenylnaphthalene

There total 6 articles about 1-Iodo-8-phenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,8-diiodonaphthalene (1730-04-7) + phenylboronic acid (98-80-6) → 1-iodo-8-phenylnaphthalene (25308-69-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate;

DOI:10.1039/c4nj00735b

Reference yield: 40.0%

1,8-diiodonaphthalene (1730-04-7) + phenylboronic acid (98-80-6) → 1-iodo-8-phenylnaphthalene (25308-69-4) + 1,8-diphenylnaphthalene (1038-67-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; for 24h; Reflux; Inert atmosphere;

DOI:10.1016/j.tetasy.2014.12.008

Reference yield:

naphthalene-1,8-diamine (479-27-6) → 1-iodo-8-phenylnaphthalene (25308-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaNO₂, aq. H₂SO₄, (ii) aq. KI

2: (i) CuBr, (ii) O₂, H₂O

DOI:10.1021/jo00972a017

upstream raw materials:

1,8-diiodonaphthalene

cyclohexanone

phenyllithium

naphthalene-1,8-diamine

Downstream raw materials:

1-(8-Phenyl-naphthalen-1-yl)-ethanol

1,8-diphenylnaphthalene

4-(8-phenylnaphthalen-1-yl)benzaldehyde

(E)-1-[4-(2-(2,4,6-tri-tert-butylphenyl)phosphaethenyl)phenyl]-8-phenylnaphthalene