9-Hydroxy-2-nonanone

Base Information

• Chemical Name: 9-Hydroxy-2-nonanone
• CAS No.: 25368-56-3
• Molecular Formula: C9H18O2
• Molecular Weight: 158.241
• Hs Code.: 2914400090
• Mol file: 25368-56-3.mol

Synonyms:9-Hydroxy-nonan-2-on;8-oxononan-1-ol;Nonanol-(9)-on-(2);9-Hydroxy-2-nonanone;2-Nonanone,9-hydroxy;9-hydroxy-nonan-2-one;

Chemical Property of 9-Hydroxy-2-nonanone

Chemical Property:

• Melting Point: 23-23.5 °C
• Boiling Point: 268.9±23.0 °C(Predicted)
• PKA: 15.19±0.10(Predicted)
• PSA: 37.30000
• Density: 0.921±0.06 g/cm3(Predicted)
• LogP: 1.90830

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-Hydroxy-2-nonanone

There total 17 articles about 9-Hydroxy-2-nonanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

8-oxo-1-nonanal (61720-56-7) → 9-hydroxy-2-nonanone (25368-56-3)

Guidance literature:

With acetylacetonatodicarbonylrhodium(l); trifluorormethanesulfonic acid; carbon monoxide; N-(5-diphenylphosphanylpyrrole-2-carbonyl)guanidine; hydrogen; In dichloromethane; at 40 ℃; for 20h; under 15001.5 Torr; Autoclave;

DOI:10.1002/anie.200903620

Reference yield: 97.0%

C12H22O4 (1339804-13-5) → 9-hydroxy-2-nonanone (25368-56-3)

Guidance literature:

With water; potassium hydroxide; In methanol; at 20 ℃; Inert atmosphere; Reflux;

DOI:10.1021/jm200944b

Reference yield: 95.0%

carbon monoxide (201230-82-2) + (E)-8-oxo-non-2-enoic acid (40980-02-7) → 9-hydroxy-2-nonanone (25368-56-3)

Guidance literature:

With dicarbonylacetylacetonato rhodium (I); N-(3-diphenylphosphanylbenzoyl)guanidine; hydrogen; In dichloromethane; at 40 ℃; for 29h; under 11251.1 Torr; chemoselective reaction; Autoclave;

DOI:10.1039/c3cc45547e

upstream raw materials:

8-hydroxyoctanenitrile

methylmagnesium bromide

sodium ethyl acetylacetate enolate

8-oxo-1-nonanal

Downstream raw materials:

non-8-en-1-ol

non-8-en-2-one

non-7-en-1-ol

cis-1-acetyl-2-methylcyclohexane