Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.

Base Information

• Chemical Name: Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.
• CAS No.: 76296-71-4
• Molecular Formula: C₃₉H₆₂O₁₂
• Molecular Weight: 722.914
• Mol file: 76296-71-4.mol

Synonyms:a-D-Glucopyranoside,(3a,25R)-spirost-5-en- 3-yl 3-O-(6-deoxy-R-L-mannopyranosyl)-;

Chemical Property of Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.

Chemical Property:

• Vapor Pressure: 1.55E-33mmHg at 25°C
• Melting Point: 189-192℃
• Refractive Index: 1.605
• Boiling Point: 849.1 °C at 760 mmHg
• Flash Point: 467.3 °C
• PSA: 176.76000
• Density: 1.34 g/cm³
• LogP: 2.38990

Purity/Quality:

≥98% ^*data from raw suppliers

Polyphyllin C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.

There total 3 articles about Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

melongoside H (89203-43-0) → C39H62O12 (76296-71-4,94271-04-2) + melongoside F (94805-85-3) + diosgenin (470-05-3,470-06-4,512-04-9,512-06-1,31356-47-5,51195-66-5,66289-52-9,89299-45-6,125710-71-6) + trillin (14144-06-0,14270-72-5,26234-60-6,26671-89-6,29685-51-6,60134-72-7,60134-73-8,66289-51-8,109008-10-8,114248-08-7)

Guidance literature:

With sulfuric acid; In methanol; for 1.5h;

DOI:10.1007/BF00580069

Reference yield:

C63H90O27 → C39H62O12 (76296-71-4,94271-04-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 260 mg / NaI, chlorotrimethylsilane / acetonitrile / 0.5 h / Ambient temperature

2: 234 mg / 10percent NaOH / methanol / 4 h / 100 °C

3: 1percent H₂SO₄ / methanol / 1.5 h

With sodium hydroxide; chloro-trimethyl-silane; sulfuric acid; sodium iodide; In methanol; acetonitrile;

DOI:10.1007/BF00580069

Reference yield:

C63H90O26 (89202-79-9) → C39H62O12 (76296-71-4,94271-04-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 234 mg / 10percent NaOH / methanol / 4 h / 100 °C

2: 1percent H₂SO₄ / methanol / 1.5 h

With sodium hydroxide; sulfuric acid; In methanol;

DOI:10.1007/BF00580069

upstream raw materials:

melongoside H

C₆₃H₉₀O₂₆

Refernces