1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione

Base Information

Chemical Name:1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione
CAS No.:257938-99-1
Molecular Formula:C10H7ClN2O4
Molecular Weight:254.62700
Hs Code.:
DSSTox Substance ID:DTXSID10579717
Nikkaji Number:J1.892.663F
Wikidata:Q82470325
Mol file:257938-99-1.mol

Synonyms:257938-99-1;1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione;(2,5-dioxopyrrolidin-1-yl) 6-chloropyridine-3-carboxylate;2,5-dioxopyrrolidin-1-yl 6-chloronicotinate;DTXSID10579717;A1-58493

Suppliers and Price of 1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione

Chemical Property:

PSA：76.57000
LogP:0.89370
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:254.0094344
Heavy Atom Count:17
Complexity:344

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)C2=CN=C(C=C2)Cl

Technology Process of 1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione

There total 2 articles about 1-[(6-Chloropyridine-3-carbonyl)oxy]pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 69045-79-0
2-choro-5-iodopyridine

: 17592-54-0
2,5-dioxopyrrolidin-1-yl formate

: 257938-99-1
2,5-dioxopyrrolidin-1-yl 6-chloronicotinate

Guidance literature:: With palladium diacetate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 2-methyltetrahydrofuran; at 60 ℃; for 10h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.joc.5b01119

Reference yield: 66.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 257938-99-1
2,5-dioxopyrrolidin-1-yl 6-chloronicotinate

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 48h;
DOI:10.1248/cpb.51.1399