2-HYDROXYDIBENZOTHIOPHENE

Base Information

• Chemical Name: 2-HYDROXYDIBENZOTHIOPHENE
• CAS No.: 22439-65-2
• Molecular Formula: C12H8OS
• Molecular Weight: 200.261
• Hs Code.: 2934999090
• Mol file: 22439-65-2.mol

Synonyms:2-Hydroxydibenzothiophene;3-Hydroxydiphenylenesulfide;Benzo[b]benzo[b]thiophen-2-ol;

Chemical Property of 2-HYDROXYDIBENZOTHIOPHENE

Chemical Property:

• Vapor Pressure: 4.37E-07mmHg at 25°C
• Melting Point: 158 °C
• Refractive Index: 1.799
• Boiling Point: 403.4 °C at 760 mmHg
• PKA: 9.43±0.30(Predicted)
• Flash Point: 197.8 °C
• PSA: 48.47000
• Density: 1.375 g/cm³
• LogP: 3.76010
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Dibenzothiophene-2-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-HYDROXYDIBENZOTHIOPHENE is a hydroxy derivative of dibenzothiophene. Coal model compound used in chemical coal cleaning studies with molten hydroxides.

Technology Process of 2-HYDROXYDIBENZOTHIOPHENE

There total 11 articles about 2-HYDROXYDIBENZOTHIOPHENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-bromodibenzothiophene (22439-61-8) → 2-hydroxydibenzothiophene 5,5-dioxide (22439-65-2)

Guidance literature:

With t-BuBrettPhos; C₄₄H₆₂NO₅PPdS; water; potassium hydroxide; In 1,4-dioxane; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1021/jo500662s

Reference yield: 83.0%

2-bromodibenzo[b,d]thiophene 5,5-dioxide (53846-85-8) → 2-hydroxydibenzothiophene 5,5-dioxide (22439-65-2)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium hydroxide; tert-butyl XPhos; In 1,4-dioxane; water; at 100 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.5b03384

Reference yield: 77.0%

dibenzo[b,d]thien-2-ylboronic acid (668983-97-9) → 2-hydroxydibenzothiophene 5,5-dioxide (22439-65-2)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 40 ℃;

DOI:10.1039/c0cc00211a

upstream raw materials:

2-bromodibenzothiophene

dibenzothiophen-2-ylamine

water

dibenzothiophene

Downstream raw materials:

2-hydroxy-dibenzothiophene-3-carboxylic acid

[1,1'-biphenyl]-3-ol

C₁₈H₂₀OS

2-methoxydibenzo[b,d]thiophene 5,5-dioxide