1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester

Base Information

Chemical Name:1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester
CAS No.:26001-79-6
Molecular Formula:C26H22ClNO4
Molecular Weight:447.918
Hs Code.:
Mol file:26001-79-6.mol

Synonyms:[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid benzyl ester;[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid benzyl ester;1-(4-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeurebenzylester;[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-indol-3-yl]-acetic acid benzyl ester;2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid benzyl ester;

Suppliers and Price of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester

Chemical Property:

Boiling Point:552.4±50.0 °C(Predicted)
PSA：57.53000
Density:1.23±0.1 g/cm3(Predicted)
LogP:5.58610

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester

There total 3 articles about 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 122-01-0
4-chloro-benzoyl chloride

: 3285-40-3
(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid benzyl ester

: 26001-79-6
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid benzyl ester

Guidance literature:: (5-methoxy-2-methyl-1H-indol-3-yl)acetic acid benzyl ester; With potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.5h;

4-chloro-benzoyl chloride; In tetrahydrofuran;
DOI:10.1002/ejoc.200900520

Reference yield: 88.0%

: 53-86-1
[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

: 100-51-6,185532-71-2
benzyl alcohol

: 26001-79-6
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid benzyl ester

Guidance literature:: [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid; With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; In dichloromethane; for 0.166667h; Inert atmosphere;

benzyl alcohol; In dichloromethane; for 12h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.05.063