1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-
CAS No.:262598-92-5
Molecular Formula:C25H29F3N6O3
Molecular Weight:518.539
Hs Code.:

1-Piperidinecarboxylic acid,
3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino
]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-

Synonyms:

Suppliers and Price of 1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 6 raw suppliers

Chemical Property of 1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)-

There total 1 articles about 1-Piperidinecarboxylic acid, 3-[[[2-hydroxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]amino ]-2-phenyl-, 1,1-dimethylethyl ester, (2S,3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-hydroxy-5-(5'-trifluoro-methyltetrazo-1-yl)benzaldehyde

: 187679-58-9
(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine

: 262598-92-5
(2S,3S)-1-t-butoxycarbonyl-2-phenyl-3-[2-hydroxy-5-(5'-trifluoromethyl-tetrazol-1-yl)phenylmethyleneamino]piperidine

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In 1,1-dichloroethane; ethyl acetate;

Reference yield:

: 262598-92-5
(2S,3S)-1-t-butoxycarbonyl-2-phenyl-3-[2-hydroxy-5-(5'-trifluoromethyl-tetrazol-1-yl)phenylmethyleneamino]piperidine

: 844446-46-4
[d₂-¹⁸F]-fluorobromomethane

: [¹⁸F][2-fluorodideuteromethoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-benzyl]-([2S,3S]-2-phenyl-piperidin-3-yl)-amine

Guidance literature:: (2S,3S)-1-t-butoxycarbonyl-2-phenyl-3-[2-hydroxy-5-(5'-trifluoromethyl-tetrazol-1-yl)phenylmethyleneamino]piperidine; [d₂-¹⁸F]-fluorobromomethane; With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 0 - 100 ℃; for 0.2h;

With trifluoroacetic acid; at 100 ℃; for 0.00833333h;

Reference yield:

: 262598-92-5
(2S,3S)-1-t-butoxycarbonyl-2-phenyl-3-[2-hydroxy-5-(5'-trifluoromethyl-tetrazol-1-yl)phenylmethyleneamino]piperidine

: 85725-77-5
1-bromo-2-[¹⁸F]fluoroethane

: [¹⁸][2-fluoroethoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-benzyl]-([2S,3S]-2-phenyl-piperidin-3-yl)-amine

Guidance literature:: (2S,3S)-1-t-butoxycarbonyl-2-phenyl-3-[2-hydroxy-5-(5'-trifluoromethyl-tetrazol-1-yl)phenylmethyleneamino]piperidine; 1-bromo-2-[¹⁸F]fluoroethane; With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 0 - 110 ℃; for 0.25h;

With trifluoroacetic acid; at 110 ℃; for 0.00833333h;