[Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid

Base Information

Chemical Name:[Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid
CAS No.:276695-40-0
Molecular Formula:C15H14ClNO4S
Molecular Weight:339.799
Hs Code.:
European Community (EC) Number:837-839-4
ChEMBL ID:CHEMBL2010980
Mol file:276695-40-0.mol

Synonyms:[Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid;276695-40-0;2-(N-benzyl4-chlorobenzenesulfonamido)acetic acid;2-[benzyl-(4-chlorophenyl)sulfonylamino]acetic acid;CHEMBL2010980;Cambridge id 5895791;Oprea1_224051;Oprea1_359827;BDBM50484919;MFCD01168173;AKOS000114868;CS-0218348;EN300-00649;2-(N-benzyl4-chlorobenzenesulfonamido)aceticacid;AB00100382-01;Z56891245;Glycine, N-[(4-chlorophenyl)sulfonyl]-N-(phenylmethyl)-

Suppliers and Price of [Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:339.0332068
Heavy Atom Count:22
Complexity:462

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CC(=O)O)S(=O)(=O)C2=CC=C(C=C2)Cl

Technology Process of [Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid

There total 5 articles about [Benzyl-(4-chloro-benzenesulfonyl)-amino]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 333358-73-9
N-benzyl-N-[(4-chlorophenyl)sulfonyl]glycine methyl ester

: 276695-40-0
N-benzyl-N-[(4-chlorophenyl)sulfonyl]glycine

Guidance literature:: N-benzyl-N-[(4-chlorophenyl)sulfonyl]glycine methyl ester; With sodium hydroxide; In methanol; for 1h; Reflux;

With hydrogenchloride; In water; at 20 ℃; pH=2;
DOI:10.1016/j.ejmech.2012.02.045

Reference yield:

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 276695-40-0
N-benzyl-N-[(4-chlorophenyl)sulfonyl]glycine

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / acetone; H₂O / 20 °C

2: Et₃N / acetonitrile / 2 h / Heating

With sodium hydrogencarbonate; triethylamine; In water; acetone; acetonitrile; 1: Condensation / 2: Alkylation;
DOI:10.1016/S0223-5234(00)00127-6

Reference yield:

: 10504-90-2
N-benzyl-4-chlorobenzenesulfonamide

: 276695-40-0
N-benzyl-N-[(4-chlorophenyl)sulfonyl]glycine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: sodium hydroxide / methanol / 1 h / Reflux

2.2: 20 °C / pH 2

With potassium carbonate; sodium hydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.02.045