N2-Methyl-L-arginine

Base Information

• Chemical Name: N2-Methyl-L-arginine
• CAS No.: 2480-28-6
• Molecular Formula: C₇H₁₆N₄O₂
• Molecular Weight: 188.23
• Mol file: 2480-28-6.mol

Synonyms:Arginine,N2-methyl- (7CI); Arginine, N2-methyl-, L- (8CI)

Chemical Property of N2-Methyl-L-arginine

Chemical Property:

• Vapor Pressure: 1.41E-07mmHg at 25°C
• Melting Point: 260 °C
• Boiling Point: 401.7°Cat760mmHg
• PKA: 2.41±0.24(Predicted)
• Flash Point: 196.7°C
• PSA: 111.23000
• Density: 1.32g/cm³
• LogP: 0.50410
• Storage Temp.: Store at RT
• Water Solubility.: Soluble to 100 mM in water

Purity/Quality:

98%Min ^*data from raw suppliers

N2-Methyl-L-arginine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N2-Methyl-L-arginine is an analog of L-Arginine, which is a physiological precursor for the formation of NO which mediates endothelium-dependent relaxation.

Technology Process of N2-Methyl-L-arginine

There total 8 articles about N2-Methyl-L-arginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-Methylarginin (2480-28-6)

Guidance literature:

With phosphonium iodide; hydrogen iodide; at 85 ℃; N^α-methyl-DL-arginine;

Reference yield:

(S)-5-Guanidino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid (64143-95-9) → N-monomethyl L-arginine (2480-28-6)

Guidance literature:

With hydrogen bromide; phenol; Heating;

DOI:10.1135/cccc19771233

Reference yield:

carbamimidothioic acid methyl ester (2986-19-8) → D-NMMA (2480-28-6)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

N²-methyl-DL-ornithine

carbamimidothioic acid methyl ester

formaldehyd

(S)-5-Guanidino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid

Refernces