benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate

Base Information

Chemical Name:benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate
CAS No.:17415-89-3
Molecular Formula:C₁₈H₂₂N₂O₄S
Molecular Weight:362.45
Hs Code.:
NSC Number:101193
DSSTox Substance ID:DTXSID40938474
Wikidata:Q82914787
ChEMBL ID:CHEMBL1878891

Synonyms:MLS002703597;17415-89-3;NSC101193;CHEMBL1878891;DTXSID40938474;NSC-101193;SMR001570314;Benzyl hydrogen {3-[(4-methylbenzene-1-sulfonyl)amino]propyl}carbonimidate

Suppliers and Price of benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.227g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:362.13002836
Heavy Atom Count:25
Complexity:490

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCCCNC(=O)OCC2=CC=CC=C2

Technology Process of benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate

There total 7 articles about benzyl N-[3-[(4-methylphenyl)sulfonylamino]propyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 46460-73-5
N-benzyloxycarbonyl-1,3-diaminopropane

: 98-59-9
p-toluenesulfonyl chloride

: 17415-89-3
N'-(p-Toluolsulfonyl)-N-benzyloxycarbonyl-1,3-diamino-propan

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.bmc.2020.115493 DOI:10.1016/j.bioorg.2021.105424

Reference yield:

: 174626-34-7
N-(benzyloxycarbonyl)-3-amino-1-propyl methanesulfonate

: 17415-89-3
N'-(p-Toluolsulfonyl)-N-benzyloxycarbonyl-1,3-diamino-propan

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / dimethyl sulfoxide / 2 h / 70 °C

2: triphenylphosphine / methanol / 2 h / Reflux

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C

With sodium azide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2020.115493

Reference yield:

: 34637-22-4
3-[(N-benzyloxycarbonyl)amino]propanol

: 17415-89-3
N'-(p-Toluolsulfonyl)-N-benzyloxycarbonyl-1,3-diamino-propan

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / 4 h / 0 °C

2: sodium azide / dimethyl sulfoxide / 2 h / 70 °C

3: triphenylphosphine / methanol / 2 h / Reflux

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C

With sodium azide; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2020.115493