6-Aminouridine

Base Information

• Chemical Name: 6-Aminouridine
• CAS No.: 27960-35-6
• Molecular Formula: C9H13N3O6
• Molecular Weight: 259.21600
• Mol file: 27960-35-6.mol

Synonyms:6-Amino-1-D-ribosyl-uracil;6-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione;6-aminouridine;

Chemical Property of 6-Aminouridine

Chemical Property:

• PSA: 150.80000
• LogP: -2.68850

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Aminouridine

There total 3 articles about 6-Aminouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

6-azido-uridine (101814-74-8) → 6-amino-uridine (27960-35-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; at 20 ℃; for 2h; atmospheric pressure;

DOI:10.1021/jm7010673

Reference yield: 84.0%

N6-(N,N'-dimethylformamide)-2′,3′,5′-tri-O-benzoyl-6-aminouridine → 6-amino-uridine (27960-35-6)

Guidance literature:

With ammonia; In methanol; at 60 ℃;

DOI:10.1021/acs.joc.6b00310

Reference yield:

→ 6-amino-uridine (27960-35-6)

Guidance literature:

1-Cyanoacetyl-3-<2,3,5-tri-O-benzoyl-D-ribosyl>-harnstoff, Na-Aethylat, A., Erwaermen;

DOI:10.1039/jr9640000451

upstream raw materials:

6-azido-uridine

Refernces

• 1、 -. "PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS". Page/Page column 33. . Retrieved 2008/12/07.
• 2、 -. "ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA". Page/Page column 33. . Retrieved 2008/06/13.