Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester

Base Information

Chemical Name:Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester
CAS No.:280754-15-6
Molecular Formula:C12H12N2O2S
Molecular Weight:248.305
Hs Code.:
Mol file:280754-15-6.mol

Synonyms:Ethyl-4-(thiazol-2-ylamino)benzoate;Benzoic acid,4-(2-thiazolylamino)-,ethyl ester;4-(thiazol-2-ylamino)-benzoic acid ethyl ester;

Suppliers and Price of Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester

Chemical Property:

Boiling Point:387.2±44.0 °C(Predicted)
PSA：79.46000
Density:1.289±0.06 g/cm3(Predicted)
LogP:3.13640

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester

There total 5 articles about Benzoic acid, 4-(2-thiazolylamino)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3034-52-4
2-chlorothiazole

: 94-09-7
p-aminoethylbenzoate

: 280754-15-6
ethyl 4-(thiazol-2-ylamino)benzoate

Guidance literature:: With toluene-4-sulfonic acid; In isopropyl alcohol; at 80 ℃; for 36h;
DOI:10.1016/j.bmcl.2011.01.123

Reference yield:

: 107-20-0
2-chloroethanal

: 23051-16-3
4-thioureidobenzoic acid ethyl ester

: 280754-15-6
ethyl 4-(thiazol-2-ylamino)benzoate

Guidance literature:: In ethanol; water; for 1h; Heating / reflux;

Reference yield:

: 2131-62-6
4-isothiocyanatobenzoic acid

: 280754-15-6
ethyl 4-(thiazol-2-ylamino)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / water / 6 h / 20 °C

2: 80 °C

With ammonium hydroxide; In water;
DOI:10.1021/acs.jmedchem.8b01766