N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester

Base Information

Chemical Name:N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester
CAS No.:28426-51-9
Molecular Formula:C23H26N2O5
Molecular Weight:410.47
Hs Code.:
DSSTox Substance ID:DTXSID701168183
ChEMBL ID:CHEMBL5220474

Synonyms:CHEMBL5220474;SCHEMBL18620591;DTXSID701168183;BDBM50607278;N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester;28426-51-9

Suppliers and Price of N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:410.18417193
Heavy Atom Count:30
Complexity:584

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CCCN1C(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3
Isomeric SMILES:COC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

Technology Process of N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester

There total 17 articles about N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-proline methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2133-40-6
L-proline methyl ester monohydrochloride

: 3588-57-6
Z-DL-Phe-OH

: 28426-51-9
methyl ((benzyloxy)carbonyl)-L-phenylalanyl-L-prolinate

Guidance literature:: With 4-methyl-morpholine; DMT*brucine tetrafluoroborate; brucine; In acetonitrile; at 0 - 20 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ol802691x

Reference yield: 93.0%

: 1161-13-3
N-Cbz-L-Phe

: 2133-40-6
L-proline methyl ester monohydrochloride

: 28426-51-9
methyl ((benzyloxy)carbonyl)-L-phenylalanyl-L-prolinate

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1039/b617217b