N,N,2,4,6-pentamethylbenzamide

Base Information

Chemical Name:N,N,2,4,6-pentamethylbenzamide
CAS No.:2843-93-8
Molecular Formula:C12H17NO
Molecular Weight:191.273
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60461577
Nikkaji Number:J395.063H
Wikidata:Q82285950
Mol file:2843-93-8.mol

Synonyms:N,N,2,4,6-pentamethylbenzamide;2843-93-8;SCHEMBL1004853;DTXSID60461577;AKOS013917041

Suppliers and Price of N,N,2,4,6-pentamethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N,N,2,4,6-pentamethylbenzamide

Chemical Property:

PSA：20.31000
LogP:2.31360
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:191.131014166
Heavy Atom Count:14
Complexity:200

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C)C(=O)N(C)C)C

Technology Process of N,N,2,4,6-pentamethylbenzamide

There total 4 articles about N,N,2,4,6-pentamethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 576-83-0
2,4,6-trimethylphenyl bromide

: 479486-96-9
N,N-dimethyl (trimethylsilyl)methanamide

: 2843-93-8
N,N,2,4,6-pentamethylbenzamide

Guidance literature:: bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In toluene; at 100 ℃; for 11h;
DOI:10.1021/ol0270834

Reference yield: 67.0%

: 79-44-7
N,N-Dimethylcarbamoyl chloride

: 108-67-8
1,3,5-trimethyl-benzene

: 2843-93-8
N,N,2,4,6-pentamethylbenzamide

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In nitromethane; for 3h; regioselective reaction; Inert atmosphere; Reflux;
DOI:10.1002/ejoc.201801338

Reference yield: 65.0%

: 576-83-0
2,4,6-trimethylphenyl bromide

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 2843-93-8
N,N,2,4,6-pentamethylbenzamide

Guidance literature:: 2,4,6-trimethylphenyl bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h; Further stages;
DOI:10.1016/j.tet.2012.04.016