2-Hydroxy-5-propylbenzoic acid

Base Information

Chemical Name:2-Hydroxy-5-propylbenzoic acid
CAS No.:28488-44-0
Molecular Formula:C₁₀H₁₂O₃
Molecular Weight:180.203
Hs Code.:
DSSTox Substance ID:DTXSID70544643
Wikidata:Q82421830
Mol file:28488-44-0.mol

Synonyms:2-Hydroxy-5-propylbenzoic acid;28488-44-0;SCHEMBL2534915;DTXSID70544643;QPFZHQMFWCRNPU-UHFFFAOYSA-N;AKOS011839882

Suppliers and Price of 2-Hydroxy-5-propylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Hydroxy-5-propylbenzoic acid

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:180.078644241
Heavy Atom Count:13
Complexity:179

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1=CC(=C(C=C1)O)C(=O)O

Technology Process of 2-Hydroxy-5-propylbenzoic acid

There total 6 articles about 2-Hydroxy-5-propylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.8%

: 28488-44-0
2-hydroxy-5-propylbenzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In tetrahydrofuran; water; tert-butyl alcohol; at 15 - 30 ℃; for 2.5h;

Reference yield:

: 77526-99-9
2-hydroxy-5-propionyl-benzoic acid methyl ester

: 28488-44-0
2-hydroxy-5-propylbenzoic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; mercury dichloride; zinc; Yield given. Multistep reaction; 1.) reflux, 20 h, 2.) reflux, 12 h;
DOI:10.1021/jm00142a023

Reference yield:

: 119-36-8,8024-54-2
methyl salicylate

: 28488-44-0
2-hydroxy-5-propylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / aluminum chloride / CS₂ / 12 h

2: 1.) Zn, HgCl₂, conc. aq. HCl, 2.) aq. NaOH / 1.) reflux, 20 h, 2.) reflux, 12 h

With hydrogenchloride; sodium hydroxide; aluminium trichloride; mercury dichloride; zinc; In carbon disulfide;
DOI:10.1021/jm00142a023