2-(1,2,3-Thiadiazol-4-yl)aniline

Base Information

Chemical Name:2-(1,2,3-Thiadiazol-4-yl)aniline
CAS No.:286955-98-4
Molecular Formula:C8H7N3S
Molecular Weight:177.23
Hs Code.:
DSSTox Substance ID:DTXSID70416053
Nikkaji Number:J1.324.756K
Wikidata:Q82225190
Mol file:286955-98-4.mol

Synonyms:2-(1,2,3-thiadiazol-4-yl)aniline;286955-98-4;4-(2-aminophenyl)-1,2,3-thiadiazole;Benzenamine, 2-(1,2,3-thiadiazol-4-yl)-;DTXSID70416053;2-(1,2,3-Thiadiazole-4-yl)aniline;BB 0220529;InChI=1/C8H7N3S/c9-7-4-2-1-3-6(7)8-5-12-11-10-8/h1-5H,9H

Suppliers and Price of 2-(1,2,3-Thiadiazol-4-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(1,2,3-Thiadiazol-4-yl)aniline

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:177.03606841
Heavy Atom Count:12
Complexity:153

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CSN=N2)N

Technology Process of 2-(1,2,3-Thiadiazol-4-yl)aniline

There total 2 articles about 2-(1,2,3-Thiadiazol-4-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 286955-96-2
4-(2-nitrophenyl)-1,2,3-thiadiazole

: 286955-98-4
4-(2-aminophenyl)-1,2,3-thiadiazole

Guidance literature:: With hydrazine hydrate; palladium on activated charcoal; In ethanol; for 24h; Heating;
DOI:10.1016/S0040-4020(00)00315-X

Reference yield:

: ethyl carbazone of o-nitroacetophenone

: 286955-98-4
4-(2-aminophenyl)-1,2,3-thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / SOCl₂ / 2 h / Heating

2: 78 percent / NH₂NH₂*H₂O / Pd/C / ethanol / 24 h / Heating

With thionyl chloride; hydrazine hydrate; palladium on activated charcoal; In ethanol; 1: Cyclization / 2: Reduction;
DOI:10.1016/S0040-4020(00)00315-X

Reference yield: 85.0%

: 286955-98-4
4-(2-aminophenyl)-1,2,3-thiadiazole

: 74-88-4
methyl iodide

: 2-(2-aminoethyl)ethynylsulfanylmethane

Guidance literature:: 4-(2-aminophenyl)-1,2,3-thiadiazole; With potassium tert-butylate; In tetrahydrofuran; for 0.25h;

methyl iodide; In tetrahydrofuran; for 1h;
DOI:10.1016/S0040-4020(00)00315-X