Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl-

Base Information

Chemical Name:Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl-
CAS No.:28870-36-2
Molecular Formula:C17H16N4O
Molecular Weight:292.33500
Hs Code.:
Mol file:28870-36-2.mol

Synonyms:1-amino-5-phenyl-7,8,9,10-tetrahydro-5H-pyrimido[4,5-c]isoquinolin-6-one;

Suppliers and Price of Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl-

Chemical Property:

PSA：73.80000
LogP:2.82290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl-

There total 5 articles about Pyrimido[4,5-c]isoquinolin-6(5H)-one, 1-amino-7,8,9,10-tetrahydro-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 28870-35-1
3-amino-1-oxo-2-phenyl-1,2,5,6,7,8-hexahydroisoquinoline-4-carbonitrile

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 28870-36-2
1-Amino-5-phenyl-6-oxo-5,6,7,8,9,10-hexahydropyrimido<4,5-c>isoquinoline

Guidance literature:: for 4h; Reflux;
DOI:10.1134/S1070428020110111

Reference yield:

: 35248-35-2
2-morpholin-4-yl-cyclohex-1-enecarboxylic acid anilide

: 28870-36-2
1-Amino-5-phenyl-6-oxo-5,6,7,8,9,10-hexahydropyrimido<4,5-c>isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / piperidine / ethanol / 2.5 h / Heating

2: 53 percent / 4 h / Heating

With piperidine; In ethanol;

Reference yield:

: 95606-00-1
2-Phenylcarbamoyl-cyclohexylidenomalononitrile

: 28870-36-2
1-Amino-5-phenyl-6-oxo-5,6,7,8,9,10-hexahydropyrimido<4,5-c>isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 10percent NaOH / ethanol; H₂O / 0.17 h / Heating

2: 53 percent / 4 h / Heating

With sodium hydroxide; In ethanol; water;