28870-35-1Relevant academic research and scientific papers
Synthesis and Biological Activity of Partially Hydrogenated 1-Aminopyrimido[4,5-c]isoquinoline Derivatives
Paronikyan,Dashyan, Sh. Sh.,Stepanyan
, p. 1963 - 1968 (2021/01/13)
Abstract: A one-pot synthesis of 3-amino-2-aryl-1,2,5,6,7,8-hexahydroisoquinolin-1-ones by the nucleophilic substitution at position 1 of the pyridine ring was developed. The synthesized compounds were used to prepare 1-amino-7,8,9,10-tetrahydropyrimido[4
One-pot synthesis of isothiachromene, isochromene, isoquinoline and tetrahydronaphthalene derivatives
El-Sayed,Abdel-Ghany
, p. 1233 - 1240 (2007/10/03)
A new series of tetrahydronaphthalene, isothiachromene, isochromene and isoquinoline derivatives were synthesized by reacting cyclohexylidenemalononitrile with active nitriles, active halo compounds, carbon disulfide, aldehydes, isothiocyanates and isocyanates, respectively.
The Reaction of Malononitrile with Enamines of Some Cyclic β-Keto Acid Anilides and Amidines
Bogdanowicz-Szwed, Krystyna,Policht, Andrzej
, p. 721 - 728 (2007/10/02)
The reaction of enamines 1 derivatives of cyclohexanon- or cycloheptanon-2-carboxylic acid anilides with malononitrile gave in the first step 2-phenylcarbamoyl-cycloalkylideno-malononitriles 3, which in turn were converted into 1-oxo-2-phenyl-3-amino-4-cy
The Knoevenagel Reaction of Malononitrile with Some Cyclic β-Ketocarbothionic Acid Anilides. Synthesis of Cycloalkeno-pyridines and Cycloalkeno-thiopyrans
Bogdanowicz-Szwed, Krystyna
, p. 583 - 592 (2007/10/02)
A new route to the cycloalkeno-pyridines 2 and cycloalkeno-thiopyrans 5 by the reaction of malononitrile with enamines of cyclic β-ketocarbothionic acid anilides is presented.The elucidation of the structure of compounds obtained is based on MS spectral d
Die Nitril-Carboxamid-Umlagerung
Bischoff, Christian,Schroeder, Edith,Gruendemann, Egon
, p. 519 - 525 (2007/10/02)
By reaction of cyclohexanone-2-carboxamide (4) with cyan amide 1-cyano-cyclohex-1-en-2-yl-urea (6) is formed via nitrile carboxamide rearrangement.Whilst compound 6 with 1,2-diaminobenzene hydrochloride forms 11-amino-1H-2,3,4,5-tetrahydrodibenzo1,4
Reaction of Methylene Active Nitriles and Cyanamide with Acylated Enamines
Gewald, K.,Schaefer, H.,Bellmann, P.
, p. 933 - 941 (2007/10/02)
The addition products from enamines onto isocyanates and isothiocyanates, i.e. substituted β-aminoacrylo amides 1 and thioamides 2, react with malononitrile to yield the 6-amino-1-aryl-5-cyano-pyridin-2-ones 3 and -thiones 4 among them 5,6,7,8-tetrahydroi
