Technology Process of p-Pentylbenzamidine hydrochloride
There total 2 articles about p-Pentylbenzamidine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
p-n-pentylbenzonitrile;
With
trimethylaluminum; ammonium chloride;
In
toluene;
at 80 ℃;
With
silica gel;
In
methanol; chloroform; toluene;
for 1h;
DOI:10.1021/ja034676g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaNH2 / liquid ammonia; diethyl ether / 0.5 h
1.2: liquid ammonia; diethyl ether / 3 h
2.1: Me3Al; NH4Cl / toluene / 80 °C
2.2: 0.1 g / silica gel / CHCl3; toluene; methanol / 1 h
With
trimethylaluminum; ammonium chloride; sodium amide;
In
diethyl ether; ammonia; toluene;
DOI:10.1021/ja034676g
- Guidance literature:
-
With
sodium;
In
methanol; diethyl ether; hexane; ethyl acetate;
