ETHYL 4-(2,5-DIMETHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE

Base Information

• Chemical Name: ETHYL 4-(2,5-DIMETHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE
• CAS No.: 292855-70-0
• Molecular Formula: C16H20N2O5
• Molecular Weight: 0.00000
• Mol file: 292855-70-0.mol

Synonyms:

Chemical Property of ETHYL 4-(2,5-DIMETHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE

Chemical Property:

• Melting Point: 218-219°C
• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ETHYL 4-(2,5-DIMETHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE

There total 1 articles about ETHYL 4-(2,5-DIMETHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethyl acetoacetate (141-97-9) + 2,5-dimethoxybenzaldehyde (93-02-7) + urea (57-13-6) → ethyl 6-methyl-4-(2,5-dimethoxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (292855-70-0)

Guidance literature:

With 1?(1?carboxymethyl)?3?methylimidazolium tetrafluoroborate; for 0.0416667h; Catalytic behavior; Microwave irradiation; Green chemistry;

DOI:10.1007/s12039-012-0278-5

upstream raw materials:

ethyl acetoacetate

2,5-dimethoxybenzaldehyde

urea

Refernces

• 1、 Kodape, Manisha M.,Gawhale, Nandkishor D.,Awjare, Nikita V.. "Synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) by natural L-ascorbic acid". . p. 671 - 675. Retrieved 2015/05/27.
• 2、 Cheng, Chen,Jing, Huanwang. "Bronsted acidic ionic liquids of aza-crown ether complex cations: Preparation and applications in organic reactions". . p. 34325 - 34331. Retrieved 2014/11/07.