α-[(Dimethylamino)methyl]-p-methoxybenzyl alcohol

Base Information

• Chemical Name: α-[(Dimethylamino)methyl]-p-methoxybenzyl alcohol
• CAS No.: 2970-99-2
• Molecular Formula: C₁₁H₁₇NO₂
• Molecular Weight: 195.261
• Mol file: 2970-99-2.mol

Synonyms:2-Dimethylamino-1-(4-methoxy-phenyl)-aethanol;N,N-Dimethyl-2-hydroxy-4'-methoxy-2-phenethylamin;2-Dimethylamino-1-(4-methoxy-phenyl)-ethanol;2-Dimethylamino-1-<4-methoxyphenyl>-aethanol-(1);N,N-Dimethyl-4-methoxy-β-hydroxy-phenaethylamin;α-<(Dimethylamino)-methyl>-p-methoxybenzylalkohol;

Chemical Property of α-[(Dimethylamino)methyl]-p-methoxybenzyl alcohol

Chemical Property:

• Boiling Point: 99 - 101 °C (0.1 mmHg)
• PSA: 32.70000
• LogP: 1.29020

Purity/Quality:

99% ^*data from raw suppliers

2-(Dimethylamino)-1-(4-methoxyphenyl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α-[(Dimethylamino)methyl]-p-methoxybenzyl alcohol

There total 5 articles about α-[(Dimethylamino)methyl]-p-methoxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-dimethylamino-1-(4-methoxy-phenyl)-ethanone (53250-07-0) → 2-dimethylamino-1-(4-methoxy-phenyl)-ethanol (2970-99-2)

Guidance literature:

With aluminum isopropoxide; In isopropyl alcohol;

DOI:10.1039/jr9630001385

Reference yield:

methoxybenzene (100-66-3) → 2-dimethylamino-1-(4-methoxy-phenyl)-ethanol (2970-99-2)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃ / CS₂

2: methanol

3: NaBH₄ / methanol

With sodium tetrahydroborate; aluminium trichloride; In methanol; carbon disulfide;

Reference yield:

2-chloro-1-(4-methoxyphenyl)ethanone (2196-99-8) → 2-dimethylamino-1-(4-methoxy-phenyl)-ethanol (2970-99-2)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol

2: NaBH₄ / methanol

With sodium tetrahydroborate; In methanol;

upstream raw materials:

2-dimethylamino-1-(4-methoxy-phenyl)-ethanone; hydrochloride

2-dimethylamino-1-(4-methoxy-phenyl)-ethanone

methoxybenzene

2-chloro-1-(4-methoxyphenyl)ethanone

Refernces