(2,3-Dichloro-4-acetylphenoxy)acetic acid

Base Information

Chemical Name:(2,3-Dichloro-4-acetylphenoxy)acetic acid
CAS No.:2977-54-0
Molecular Formula:C10H8Cl2O4
Molecular Weight:263.077
Hs Code.:
DSSTox Substance ID:DTXSID501263755

Synonyms:2977-54-0;acetic acid,(4-acetyl-2,3-dichlorophenoxy)-;SCHEMBL10834699;RPQOGNABCPORJO-UHFFFAOYSA-N;DTXSID501263755;(2,3-Dichloro-4-acetylphenoxy)acetic acid;FT-0766791;2-(4-acetyl-2,3-dichlorophenoxy)acetic acid;[2,3-dichloro-4-(1-oxo-ethyl)phenoxy]acetic acid

Suppliers and Price of (2,3-Dichloro-4-acetylphenoxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (2,3-Dichloro-4-acetylphenoxy)acetic acid

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:261.9799641
Heavy Atom Count:16
Complexity:282

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl

Technology Process of (2,3-Dichloro-4-acetylphenoxy)acetic acid

There total 7 articles about (2,3-Dichloro-4-acetylphenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.6%

: 2977-53-9
1-(2,3-dichloro-4-hydroxyphenyl)ethan-1-one

: 105-36-2
ethyl bromoacetate

: 2977-54-0
2-(4-acetyl-2,3-dichlorophenoxy)acetic acid

Guidance literature:: 1-(2,3-dichloro-4-hydroxyphenyl)ethan-1-one; With potassium carbonate; potassium iodide; In acetone; at 60 ℃; for 0.166667h;

ethyl bromoacetate; In acetone; for 6h;

With ethanol; potassium hydroxide; at 20 ℃; for 3h;

Reference yield:

: C₁₂H₁₂Cl₂O₄

: 2977-54-0
2-(4-acetyl-2,3-dichlorophenoxy)acetic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 0 - 27 ℃; for 5h; Inert atmosphere;
DOI:10.1039/c5ob00367a

Reference yield:

: 1984-59-4
2,3-dichloroanisole

: 2977-54-0
2-(4-acetyl-2,3-dichlorophenoxy)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

1.2: 0.92 h / 25 - 27 °C / Inert atmosphere

2.1: acetic acid; hydrogen bromide / water / 17 h / 60 - 100 °C / Inert atmosphere

3.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 0 - 27 °C / Inert atmosphere

3.2: 2 h / 80 °C / Inert atmosphere

4.1: lithium hydroxide; water / tetrahydrofuran / 5 h / 0 - 27 °C / Inert atmosphere

With aluminum (III) chloride; water; hydrogen bromide; potassium carbonate; acetic acid; lithium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1039/c5ob00367a