tris(imidazol-1-yl)phosphine

Base Information

• Chemical Name: tris(imidazol-1-yl)phosphine
• CAS No.: 73946-92-6
• Molecular Formula: C9H9 N6 P
• Molecular Weight: 0
• Mol file: 73946-92-6.mol

Synonyms:Imidazole,1,1',1''-phosphinidynetri- (6CI); Tri(imidazol-1-yl)phosphine;Tris(imidazol-1-yl)phosphine

Chemical Property of tris(imidazol-1-yl)phosphine

Chemical Property:

• Boiling Point: 492.1oC at 760 mmHg
• Flash Point: 251.4oC
• PSA: 67.05000
• LogP: 1.44770

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tris(imidazol-1-yl)phosphine

There total 4 articles about tris(imidazol-1-yl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-imidazole (288-32-4) → tri(imidazol-1-yl)phosphite (73946-92-6)

Guidance literature:

With phosphorus trichloride; In tetrahydrofuran; at 0 ℃; for 0.333333h;

DOI:10.1016/S0040-4039(00)78588-1 DOI:10.1246/bcsj.56.3483

Reference yield:

1-(Trimethylsilyl)imidazole (18156-74-6) → tri(imidazol-1-yl)phosphite (73946-92-6)

Guidance literature:

With phosphorus trichloride; In benzene; at 0 ℃; for 0.5h;

DOI:10.1080/07328319808003465

Reference yield:

1H-imidazole (288-32-4) + phosphorus trichloride (7719-12-2,52843-90-0) → tri(imidazol-1-yl)phosphite (73946-92-6)

Guidance literature:

In 1,2-dichloro-ethane; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/ejoc.200800752

upstream raw materials:

1H-imidazole

1-(Trimethylsilyl)imidazole

phosphorus trichloride

Downstream raw materials:

C₃₇H₃₇N₆O₇P

Refernces

• 1、 Shimidzu, Takeo,Yamana, Kazushige,Nakamichi, Kikumi,Murakami, Akira. "Uridine Oligonucleotide Synthesis by the Reaction of Uridine with Tri-(imidazol-1-yl)phosphine". . p. 2294 - 2298. Retrieved 1981.
• 2、 Lakshman, Mahesh K.,Choudhury, Asad,Bae, Suyeal,Rochttis, Eliezer,Pradhan, Padmanava,Kumar, Amit. "Synthesis of N6,N6-dialkyladenine nucleosides using hexaalkylphosphorus triamides produced in situ". experimental part. p. 152 - 159. Retrieved 2009/07/05.
• 3、 Ivanova, Irina A.,Ross, Andrew J.,Ferguson, Michael A. J.,Nikolaev, Andrei V.. "Parasite glycoconjugates. Part 9. Synthesis of dec-9-enyl β-D-galactopyranosyl-(1→4)-α-D-mannopyranosyl phosphate and its epimers at the D-galactose moiety, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania". . p. 1743 - 1753. Retrieved 2007/10/03.