4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine

Base Information

Chemical Name:4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine
CAS No.:301219-20-5
Molecular Formula:C₁₇H₂₃N₃
Molecular Weight:269.39
Hs Code.:
DSSTox Substance ID:DTXSID60592698
Wikidata:Q82486945
Mol file:301219-20-5.mol

Synonyms:4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine;301219-20-5;SCHEMBL5764148;DTXSID60592698;DA-07187

Suppliers and Price of 4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:269.189197746
Heavy Atom Count:20
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C(=CC(=N1)C2CCNCC2)CC3=CC=CC=C3

Technology Process of 4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine

There total 5 articles about 4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 313512-98-0
4-(5-benzyl-1-ethyl-(1H)-pyrazol-3-yl)-1-(t-butoxycarbonyl)piperidine

: 301219-20-5
4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)-piperidine

Guidance literature:: With methoxybenzene; trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2003.12.004

Reference yield:

: 6629-60-3
ethylhydrazine oxalic acid salt

: 301219-16-9
4-(1-(t-butoxycarbonyl)piperidin-4-yl)-1-phenyl-2-butanon-3-yne

: 301219-18-1
4-(3-benzyl-1-ethyl-pyrazol-5-yl)piperidine

: 301219-20-5
4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)-piperidine

Guidance literature:: ethylhydrazine oxalic acid salt; 4-(1-(t-butoxycarbonyl)piperidin-4-yl)-1-phenyl-2-butanon-3-yne; In ethanol; at 60 - 80 ℃;

With hydrogenchloride; In methanol;
DOI:10.1016/j.bmcl.2003.12.006

Reference yield:

: 103-80-0
phenylacetyl chloride

: 301219-20-5
4-(5-benzyl-1-ethyl-1H-pyrazol-3-yl)-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: Pd(PPh₃)4 / 1,2-dichloro-ethane / Heating

2.1: ethanol / 60 - 80 °C

2.2: HCl / methanol

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; 1,2-dichloro-ethane;
DOI:10.1016/j.bmcl.2003.12.006