4-Chloro-3-methylpicolinic acid

Base Information

• Chemical Name: 4-Chloro-3-methylpicolinic acid
• CAS No.: 30235-20-2
• Molecular Formula: C7H6ClNO2
• Molecular Weight: 171.58100
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID401263538
• Mol file: 30235-20-2.mol

Synonyms:30235-20-2;4-CHLORO-3-METHYLPICOLINIC ACID;4-CHLORO-3-METHYLPYRIDINE-2-CARBOXYLIC ACID;4-CHLORO-3-METHYL-2-PYRIDINECARBOXYLIC ACID;2-Pyridinecarboxylic acid, 4-chloro-3-methyl-;SCHEMBL231248;DTXSID401263538;4-CHLORO-3-METHYLPICOLINICACID;AKOS005264563;AB52815;AT37426;BS-22250;CS-0210567;EN300-103926;A849879

Chemical Property of 4-Chloro-3-methylpicolinic acid

Chemical Property:

• PSA: 50.19000
• LogP: 1.74160
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 171.0087061
• Heavy Atom Count: 11
• Complexity: 163

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-3-methyl-2-pyridinecarboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CN=C1C(=O)O)Cl

Technology Process of 4-Chloro-3-methylpicolinic acid

There total 3 articles about 4-Chloro-3-methylpicolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-Chloro-3-methyl-pyridine-2-carboxylic acid phenylamide (133928-62-8) → 4-chloro-3-methylpicolinic acid (30235-20-2)

Guidance literature:

With sulfuric acid; for 4h; Heating;

DOI:10.1016/S0040-4020(01)96912-1

Reference yield:

4-chloro-3,N-dimethylpicolinanilide (133928-63-9) → 4-chloro-3-methylpicolinic acid (30235-20-2)

Guidance literature:

With sulfuric acid; Heating;

DOI:10.1016/S0040-4020(01)96912-1

Reference yield:

→ 4-chloro-3-methylpicolinic acid (30235-20-2)

Guidance literature:

3-Methyl-4-nitropicolinonitril (Ig), konz. HCl (894, 895);

upstream raw materials:

4-Chloro-3-methyl-pyridine-2-carboxylic acid phenylamide

4-chloro-3,N-dimethylpicolinanilide