133928-63-9

Basic information

• Product Name: 4-chloro-3,N-dimethylpicolinanilide
• CAS NO: 133928-63-9
• Molecular Weight: 260.723
• Mol File: 133928-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-3,N-dimethylpicolinanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-3,N-dimethylpicolinanilide(133928-63-9)
• EPA Substance Registry System: 4-chloro-3,N-dimethylpicolinanilide(133928-63-9)

Safety Data

• Hazardous Substances Data: 133928-63-9(Hazardous Substances Data)

Upstream product

• 133928-61-7 N-phenyl-4-chloro-2-pyridinecarboxamide 
• 74-88-4 methyl iodide 

Downstream Products

• 30235-20-2 4-chloro-3-methylpicolinic acid 

Relevant articles and documents

Application of organolithium and related reagents in synthesis. Part 9. Synthesis and metallation of 4-chloropicolin- and 2-chloroisonicotinanilides. A useful method for preparation of 2,3,4-trisubstituted pyridines

The synthesis and metallation (nBuLi) of 4-chloropicolin- and 2-chloroisonicotinanilides (1) and (2) as a way of regiospecific transformation of picolinic and isonicotinic acids into 2,3,4-trisubstituted pyridines (9) and (10), is described. The anilide moiety (masking group) of the formed C3-substituted chloro-anilides (9) and (10) appeared to be effectively removable on acid hydrolysis.