Aspartylcyclohexylamine

Base Information

Chemical Name:Aspartylcyclohexylamine
CAS No.:30239-40-8
Molecular Formula:C10H18N2O3
Molecular Weight:214.265
Hs Code.:
DSSTox Substance ID:DTXSID10443742
Nikkaji Number:J981.697F
Wikidata:Q82261684
Mol file:30239-40-8.mol

Synonyms:aspartylcyclohexylamine;30239-40-8;SCHEMBL3336177;DTXSID10443742;N-Cyclohexyl-L-aspartic acid alpha-amide

Suppliers and Price of Aspartylcyclohexylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of Aspartylcyclohexylamine

Chemical Property:

XLogP3:-2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:214.13174244
Heavy Atom Count:15
Complexity:237

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)C(CC(=O)O)N
Isomeric SMILES:C1CCC(CC1)NC(=O)[C@H](CC(=O)O)N

Technology Process of Aspartylcyclohexylamine

There total 3 articles about Aspartylcyclohexylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-91-8,157973-60-9
cyclohexylamine

: 30239-40-8
L-aspartic acid α-(cyclohexylamide)

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / N-methylmorpholine, isobutyl chloroformate / dimethylformamide / 1 h / -15 °C

2: 86 percent / hydrogen / Pd/C / acetic acid / 3800 Torr

With 4-methyl-morpholine; hydrogen; isobutyl chloroformate; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ac50058a011

Reference yield:

: 108-91-8,157973-60-9
cyclohexylamine

: 30239-40-8
L-aspartic acid α-(cyclohexylamide)

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / Pd / methanol

With hydrogen; palladium; In methanol;
DOI:10.1021/jm00300a046

Reference yield:

: 108-91-8,157973-60-9
cyclohexylamine

: 4515-23-5
N-benzyloxycarbonyl-L-aspartic acid anhydride

: 36314-31-5
N-(L-β-aspartyl)cyclohexylamine

: 30239-40-8
L-aspartic acid α-(cyclohexylamide)

Guidance literature:: With hydrogen; triethylamine; palladium; Yield given. Multistep reaction. Title compound not separated from byproducts; 1) THF, room temperature, 2) CH₃CO₂H;
DOI:10.1246/bcsj.57.3167