2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine

Base Information

• Chemical Name: 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine
• CAS No.: 5969-58-4
• Molecular Formula: C₂₁H₂₈N₃O₃P
• Molecular Weight: 401.445
• DSSTox Substance ID: DTXSID30387038
• Mol file: 5969-58-4.mol

Synonyms:5969-58-4;2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine;AC1MEIW9;CBMicro_039448;Oprea1_583941;Oprea1_593263;DTXSID30387038;BIM-0039482.P001

Chemical Property of 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine

Chemical Property:

• Vapor Pressure: 4.19E-10mmHg at 25°C
• Boiling Point: 499.3°Cat760mmHg
• Flash Point: 255.8°C
• Density: 1.19g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 346.14814140
• Heavy Atom Count: 26
• Complexity: 481

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=NC3=CC=CC=C3NC(C2)C4=CC=C(C=C4)F

Technology Process of 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine

There total 1 articles about 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-diphenyl-propane-1,2,3-trione (643-75-4) + Hexamethylphosphorous triamide (1608-26-0) → C21H28N3O3P (5969-58-4)

Guidance literature:

In dichloromethane;

DOI:10.1021/ja01000a051

upstream raw materials:

1,3-diphenyl-propane-1,2,3-trione

Hexamethylphosphorous triamide