2-CHLORO-3-FLUOROQUINOXALINE

Base Information

• Chemical Name: 2-CHLORO-3-FLUOROQUINOXALINE
• CAS No.: 303762-31-4
• Molecular Formula: C8H4ClFN2
• Molecular Weight: 0.00000
• Mol file: 303762-31-4.mol

Synonyms:

Chemical Property of 2-CHLORO-3-FLUOROQUINOXALINE

Chemical Property:

• Melting Point: 88-89 °C
• Boiling Point: 263.0±35.0 °C(Predicted)
• PKA: -4.90±0.48(Predicted)
• PSA: 0.00000
• Density: 1.447±0.06 g/cm3(Predicted)
• LogP: 0.00000

Purity/Quality:

2-Chloro-3-fluoroquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-CHLORO-3-FLUOROQUINOXALINE

There total 1 articles about 2-CHLORO-3-FLUOROQUINOXALINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

2,3-dichloroquinoxaline (2213-63-0) → 2-chloro-3-fluoroquinoxaline (303762-31-4) + 2,3-difluoroquinoxaline (7066-36-6)

Guidance literature:

With triethylamine; 1,8-bis(dimethylamino)naphthalene tris(hydrogen fluoride); at 80 ℃; for 105h;

DOI:10.1016/S0040-4039(00)01054-6

upstream raw materials:

2,3-dichloroquinoxaline

Refernces

• 1、 Darabantu, Mircea,Lequeux, Thierry,Pommelet, Jean-Claude,Plé, Nelly,Turck, Alain. "Selective fluorination by halogen exchange of chlorodiazines and chloropyridines promoted by the 'proton sponge' - Triethylamine tris(hydrogen fluoride) system". . p. 739 - 750. Retrieved 2007/10/03.