6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide

Base Information

Chemical Name:6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide
CAS No.:84332-04-7
Molecular Formula:C₁₄H₂₂N₄O₂
Molecular Weight:278.354
Hs Code.:2933990090
DSSTox Substance ID:DTXSID601004621
Mol file:84332-04-7.mol

Synonyms:84332-04-7;BRN 5560155;6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide;6-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-4-methoxynicotinamide;2-(2-Amino-4-methoxy-5-pyridyl-carboxamidomethyl)-1-ethylpyrrolidine;Nicotinamide, 6-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-;3-Pyridinecarboxamide, 6-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-;DTXSID601004621;LS-96370;N-[(1-Ethylpyrrolidin-2-yl)methyl]-6-imino-4-methoxy-1,6-dihydropyridine-3-carboximidic acid

Suppliers and Price of 6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide

Chemical Property:

Vapor Pressure:4.72E-09mmHg at 25°C
Boiling Point:471.3°Cat760mmHg
Flash Point:238.8°C
PSA：84.70000
Density:1.147g/cm³
LogP:1.32930
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:278.17427596
Heavy Atom Count:20
Complexity:326

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=CN=C(C=C2OC)N

Technology Process of 6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide

There total 3 articles about 6-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxynicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 84332-03-6
2-(2-chloro-4-methoxy-5-pyridyl-carboxamidomethyl)-1-ethylpyrrolidine

: 84332-04-7
2-(2-amino-4-methoxy-5-pyridyl-carboxamidomethyl)-1-ethylpyrrolidine

Guidance literature:: With ammonia; sodium; ammonium chloride; ferric nitrate; 1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.;

Reference yield:

: 26116-12-1
1-ethyl-2-pyrrolidinemethanamine

: 84332-04-7
2-(2-amino-4-methoxy-5-pyridyl-carboxamidomethyl)-1-ethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / H₂O / 12 h / Ambient temperature

2: 45 percent / 1.) liquid NH₃, Na, Fe(NO₃)3; 2.) NH₄Cl / 1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.

With ammonia; sodium; ammonium chloride; ferric nitrate; In water;

Reference yield:

: 84332-02-5
methyl 6-chloro-4-methoxypyridine-3-carboxylate

: 84332-04-7
2-(2-amino-4-methoxy-5-pyridyl-carboxamidomethyl)-1-ethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / H₂O / 12 h / Ambient temperature

2: 45 percent / 1.) liquid NH₃, Na, Fe(NO₃)3; 2.) NH₄Cl / 1.) 1 h, dioxane; 2.) 1 h, reflux; 2 h, room temp.

With ammonia; sodium; ammonium chloride; ferric nitrate; In water;