3-(Tert-butoxy)cyclobutan-1-one

Base Information

Chemical Name:3-(Tert-butoxy)cyclobutan-1-one
CAS No.:30830-28-5
Molecular Formula:C8H14O2
Molecular Weight:142.198
Hs Code.:
DSSTox Substance ID:DTXSID301293633
Nikkaji Number:J2.981.887H
Mol file:30830-28-5.mol

Synonyms:3-(tert-butoxy)cyclobutan-1-one;30830-28-5;3-(tert-Butoxy)cyclobutanone;3-[(2-methylpropan-2-yl)oxy]cyclobutan-1-one;3-(t-Butoxy)cyclobutanone;SCHEMBL9135698;URYFBVQQZFUJSM-UHFFFAOYSA-N;DTXSID301293633;3-(1,1-Dimethylethoxy)cyclobutanone;MFCD21755801;AKOS015711595;AS-60686;3-(tert-butoxy)cyclobutanone(WXC07956);EN300-128416;W15905;F8880-1612

Suppliers and Price of 3-(Tert-butoxy)cyclobutan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(Tert-butoxy)cyclobutan-1-one

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:142.099379685
Heavy Atom Count:10
Complexity:136

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC1CC(=O)C1

Technology Process of 3-(Tert-butoxy)cyclobutan-1-one

There total 2 articles about 3-(Tert-butoxy)cyclobutan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 463-51-4
Ketene

: 926-02-3
tert-butyl vinyl ether

: 30830-28-5
3-[(1,1-dimethylethyl)oxy]cyclobutanone

Guidance literature:: With zinc(II) chloride; In acetonitrile;
DOI:10.1021/jo00193a034

Reference yield:

: 926-02-3
tert-butyl vinyl ether

: 30830-28-5
3-[(1,1-dimethylethyl)oxy]cyclobutanone

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine / tert-butyl methyl ether / 1.75 h / 45 °C / Inert atmosphere

2: pyridine; palladium 10% on activated carbon; hydrogen / water; ethyl acetate / 24 h / 23 °C / 2068.65 Torr

With 4-methyl-morpholine; pyridine; palladium 10% on activated carbon; hydrogen; In tert-butyl methyl ether; water; ethyl acetate;
DOI:10.1016/j.tetlet.2011.06.027

Reference yield:

: 30830-28-5
3-[(1,1-dimethylethyl)oxy]cyclobutanone

: 103-49-1
dibenzylamine

: 1321892-03-8
cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In ethyl acetate; at 0 - 25 ℃; for 3h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.06.027