cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Base Information

Chemical Name:cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine
CAS No.:1321892-03-8
Molecular Formula:C₂₂H₂₉NO
Molecular Weight:323.478
Hs Code.:

Synonyms:cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Suppliers and Price of cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

There total 2 articles about cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 926-02-3
tert-butyl vinyl ether

: 1321892-03-8
cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methyl-morpholine / tert-butyl methyl ether / 1.75 h / 45 °C / Inert atmosphere

2: pyridine; palladium 10% on activated carbon; hydrogen / water; ethyl acetate / 24 h / 23 °C / 2068.65 Torr

3: sodium tris(acetoxy)borohydride; acetic acid / ethyl acetate / 3 h / 0 - 25 °C / Inert atmosphere

With 4-methyl-morpholine; pyridine; palladium 10% on activated carbon; hydrogen; sodium tris(acetoxy)borohydride; acetic acid; In tert-butyl methyl ether; water; ethyl acetate;
DOI:10.1016/j.tetlet.2011.06.027

Reference yield:

: 30830-28-5
3-[(1,1-dimethylethyl)oxy]cyclobutanone

: 103-49-1
dibenzylamine

: 1321892-03-8
cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In ethyl acetate; at 0 - 25 ℃; for 3h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.06.027

Reference yield: 72.0%

: 1321892-03-8
cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine

: 1321892-04-9
cis-3-[bis(phenylmethyl)amino]cyclobutanol

Guidance literature:: cis-3-[(1,1-dimethylethyl)oxy]-N,N-bis(phenylmethyl)cyclobutanamine; With hydrogenchloride; water; at 50 ℃; for 2h; Cooling with ice;

With sodium hydroxide; In water; pH=10;
DOI:10.1016/j.tetlet.2011.06.027