3-(Diethylsulfamoyl)-4-fluorobenzoic acid

Base Information

Chemical Name:3-(Diethylsulfamoyl)-4-fluorobenzoic acid
CAS No.:311785-50-9
Molecular Formula:C₁₁H₁₄FNO₄S
Molecular Weight:275.301
Hs Code.:
European Community (EC) Number:843-705-6
Mol file:311785-50-9.mol

Synonyms:3-(diethylsulfamoyl)-4-fluorobenzoic acid;311785-50-9;3-Diethylsulfamoyl-4-fluoro-benzoic acid;3-diethylsulfamoyl-4-fluorobenzoic acid;Oprea1_355109;AKOS000114762;3-(diethylsulfamoyl)-4-fluorobenzoicacid;CS-0218247;EN300-00453;SR-01000516964;J-018267;SR-01000516964-1;Z56795145

Suppliers and Price of 3-(Diethylsulfamoyl)-4-fluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-(Diethylsulfamoyl)-4-fluorobenzoic acid

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:275.06275726
Heavy Atom Count:18
Complexity:388

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1=C(C=CC(=C1)C(=O)O)F

Technology Process of 3-(Diethylsulfamoyl)-4-fluorobenzoic acid

There total 2 articles about 3-(Diethylsulfamoyl)-4-fluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 456-22-4
4-Fluorobenzoic acid

: 311785-50-9
3-(N,N-diethylsulfamoyl)-4-fluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 4 h / 140 °C

2: ethyl acetate / 24 h / 20 °C

With chlorosulfonic acid; In ethyl acetate;
DOI:10.1021/jm049141s

Reference yield:

: 2267-40-5
3-chlorosulfonyl-4-fluoro-benzoic acid

: 109-89-7
diethylamine

: 311785-50-9
3-(N,N-diethylsulfamoyl)-4-fluorobenzoic acid

Guidance literature:: In ethyl acetate; at 20 ℃; for 24h;
DOI:10.1021/jm049141s

Reference yield:

: 311785-50-9
3-(N,N-diethylsulfamoyl)-4-fluorobenzoic acid

: 849333-62-6
2-(3-diethylsulfamoyl-4-fluoro-benzoylamino)-benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride; DMF / Heating

2: pyridine / 24 h / 20 °C

3: aq. NaOH / methanol; tetrahydrofuran

With pyridine; sodium hydroxide; thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; methanol;
DOI:10.1021/jm049141s