ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate

Base Information

Chemical Name:ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate
CAS No.:315246-58-3
Molecular Formula:C15H15N3O3
Molecular Weight:285.29800
Hs Code.:
Mol file:315246-58-3.mol

Synonyms:ethyl 6-amino-5-cyano-2-methyl-4-pyridin-3-yl-4H-pyran-3-carboxylate;6-Amino-5-cyano-2-methyl-4-pyridin-3-yl-4H-pyran-3-carboxylic acid ethyl ester;

Suppliers and Price of ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Aronis compounds
ethyl6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate
20mg
$ 30.00

Total 1 raw suppliers

Chemical Property of ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate

Chemical Property:

Melting Point:141 - 143 °C
PSA：98.23000
LogP:2.42668

Purity/Quality:: ethyl6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate ^*data from reagent suppliers

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Technology Process of ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate

There total 3 articles about ethyl 6-amino-5-cyano-2-methyl-4-(3-pyridinyl)-4H-pyran-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 500-22-1
3-pyridinecarboxaldehyde

: 141-97-9
ethyl acetoacetate

: 109-77-3
malononitrile

: 315246-58-3
ethyl 6-amino-5-cyano-2-methyl-4-(pyridin-3-yl)-4H-pyran-3-carboxylate

Guidance literature:: With triethanolammonium3-hydroxypropane-1-sulfonate; at 20 ℃; for 0.333333h; Green chemistry;
DOI:10.1016/j.molliq.2019.111358

Reference yield: 72.0%

: 7424-56-8
2-(3-pyridylmethylene)malononitrile

: 141-97-9
ethyl acetoacetate

: 315246-58-3
ethyl 6-amino-5-cyano-2-methyl-4-(pyridin-3-yl)-4H-pyran-3-carboxylate

Guidance literature:: With piperidine; In ethanol; Heating;

Reference yield:

: 500-22-1
3-pyridinecarboxaldehyde

: 315246-58-3
ethyl 6-amino-5-cyano-2-methyl-4-(pyridin-3-yl)-4H-pyran-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / ethanol / 20 °C

2: 3.0 g / piperidine / ethanol / 20 °C

With piperidine; In ethanol; 1: Knoevenagel condensation / 2: Michael reaction;
DOI:10.1016/j.bmc.2004.11.020