Propanedinitrile, (3-phenylpropylidene)-

Base Information

• Chemical Name: Propanedinitrile, (3-phenylpropylidene)-
• CAS No.: 321533-39-5
• Molecular Formula: C12H10N2
• Molecular Weight: 182.225
• Mol file: 321533-39-5.mol

Synonyms:

Chemical Property of Propanedinitrile, (3-phenylpropylidene)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanedinitrile, (3-phenylpropylidene)-

There total 3 articles about Propanedinitrile, (3-phenylpropylidene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-phenyl-propionaldehyde (104-53-0) + malononitrile (109-77-3) → 2-(3-phenylpropylidene)malononitrile (321533-39-5)

Guidance literature:

With 1,2-ethanediammonium 3-hydroxypropane-1-sulfonate; In neat (no solvent); at 60 ℃; for 0.75h; Green chemistry;

DOI:10.1007/s11164-017-2998-0

Reference yield: 86.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + carbon monoxide (201230-82-2) + malononitrile (109-77-3) → 2-(3-phenylpropylidene)malononitrile (321533-39-5) + 2-(2-phenylpropyl)propanedinitrile (154323-66-7) + 2-(2-phenylpropylidene)propanedinitrile (88106-71-2) + (3-phenylpropylidene)propanedinitrile (108139-26-0)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; hydrogen; sodium 3-(diphenylphosphanyl)benzenesulfonate; In tetrahydrofuran; 1,2-dichloro-ethane; at 80 ℃; for 14h; under 31053.1 Torr;

DOI:10.1002/ejoc.200801258

Reference yield:

3-Phenyl-1-propanol (122-97-4) → 2-(3-phenylpropylidene)malononitrile (321533-39-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide / water / 9 h / 90 °C / Green chemistry

2: tungstate-loaded triazine-based magnetic poly(bis-imidazolium ionic liquid) / water / 5 h / 20 °C / Green chemistry

With dihydrogen peroxide; In water; 2: |Knoevenagel Condensation;

DOI:10.1016/j.polymer.2017.02.028

upstream raw materials:

3-phenyl-propionaldehyde

malononitrile

styrene

carbon monoxide