1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE

Base Information

Chemical Name:1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE
CAS No.:325145-36-6
Molecular Formula:C13H16N2O2
Molecular Weight:232.282
Hs Code.:2933599090
Mol file:325145-36-6.mol

Synonyms:(S)-1-Benzyl-3-ethylpiperazine-2,5-dione;(S)-1-Benzyl-3-ethyl-2,5-piperazinedione;1-Benzyl-3(S)-Ethyl-Piperazine-2,5-Dione;

Suppliers and Price of 1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione
50mg
$ 60.00

TRC
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione
10mg
$ 45.00

Crysdot
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione 95+%
10g
$ 770.00

Crysdot
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione 95+%
25g
$ 1539.00

Crysdot
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione 95+%
5g
$ 428.00

Chemenu
(3S)-1-benzyl-3-ethylpiperazine-2,5-dione 97%
10g
$ 253.00

Chemenu
(3S)-1-benzyl-3-ethylpiperazine-2,5-dione 97%
25g
$ 495.00

American Custom Chemicals Corporation
1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE 95.00%
1G
$ 1188.50

Alichem
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione
25g
$ 1539.00

Alichem
(S)-1-Benzyl-3-ethylpiperazine-2,5-dione
10g
$ 754.60

Total 12 raw suppliers

Chemical Property of 1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE

Chemical Property:

Vapor Pressure:3.35E-10mmHg at 25°C
Boiling Point:501.8±50.0 °C(Predicted)
PKA:13.78±0.40(Predicted)
PSA：49.41000
Density:1.147±0.06 g/cm3(Predicted)
LogP:1.19030
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(S)-1-Benzyl-3-ethylpiperazine-2,5-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE

There total 3 articles about 1-BENZYL-3(S)-ETHYL-PIPERAZINE-2,5-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6436-90-4
ethyl 2-(benzylamino)acetate

: 34306-42-8
Boc-Abu

: 325145-36-6
(3S)-3-ethyl-1-(phenylmethyl)-2,5-piperazinedione

Guidance literature:: ethyl 2-(benzylamino)acetate; Boc-Abu; With dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 3h;

With trifluoroacetic acid; In dichloromethane; for 1h;

Reference yield:

: 6436-90-4
ethyl 2-(benzylamino)acetate

: 325145-36-6
(3S)-3-ethyl-1-(phenylmethyl)-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 2 steps

1: DCC / CH₂Cl₂ / 18 h

2: 1.) aq. HCl, 2.) aq. NaHCO₃ / 1.) CHCl₃

With hydrogenchloride; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1021/jm9508090