(6-Chloro-2-phenylpyrimidin-4-yl)methanol

Base Information

Chemical Name:(6-Chloro-2-phenylpyrimidin-4-yl)methanol
CAS No.:325685-75-4
Molecular Formula:C11H9ClN2O
Molecular Weight:220.658
Hs Code.:2933599090
Mol file:325685-75-4.mol

Synonyms:4-Chloro-6-hydroxymethyl-2-phenylpyrimidine;chlorophenylpyrimidinylmethanol;(6-chloro-2-phenyl-pyrimidin-4-yl)-methanol;

Suppliers and Price of (6-Chloro-2-phenylpyrimidin-4-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(6-Chloro-2-phenylpyrimidin-4-yl)methanol >95%
500mg
$ 645.00

Crysdot
(6-Chloro-2-phenylpyrimidin-4-yl)methanol 95+%
1g
$ 678.00

AK Scientific
(6-Chloro-2-phenylpyrimidin-4-yl)methanol
500mg
$ 920.00

Total 8 raw suppliers

Chemical Property of (6-Chloro-2-phenylpyrimidin-4-yl)methanol

Chemical Property:

Boiling Point:290.0±22.0 °C(Predicted)
PKA:12.32±0.10(Predicted)
PSA：46.01000
Density:1.321±0.06 g/cm3(Predicted)
LogP:2.28930

Purity/Quality:

98%min ^*data from raw suppliers

(6-Chloro-2-phenylpyrimidin-4-yl)methanol >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6-Chloro-2-phenylpyrimidin-4-yl)methanol

There total 5 articles about (6-Chloro-2-phenylpyrimidin-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 325685-59-4
4-chloro-6-methoxymethyl-2-phenylpyrimidine

: 325685-75-4
4-Chloro-6-hydroxymethyl-2-phenylpyrimidine

Guidance literature:: With boron tribromide; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b00933

Reference yield:

: 1670-14-0
benzamidine monohydrochloride

: 325685-75-4
4-Chloro-6-hydroxymethyl-2-phenylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaOMe / methanol; ethanol / 21 h / Heating

2.1: 29.0 g / POCl₃ / 3 h / Heating

3.1: BBr₃ / CH₂Cl₂ / 3 h / -12 - 0 °C

3.2: 99 percent / H₂O / diethyl ether; CH₂Cl₂ / 2 h / 20 °C

With sodium methylate; boron tribromide; trichlorophosphate; In methanol; ethanol; dichloromethane;
DOI:10.1002/1521-3765(20001117)6:22<4124::AID-CHEM4124>3.0.CO;2-M

Reference yield:

: 127958-19-4
4-(methoxymethyl)-2-phenylpyrimidine

: 325685-75-4
4-Chloro-6-hydroxymethyl-2-phenylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 29.0 g / POCl₃ / 3 h / Heating

2.1: BBr₃ / CH₂Cl₂ / 3 h / -12 - 0 °C

2.2: 99 percent / H₂O / diethyl ether; CH₂Cl₂ / 2 h / 20 °C

With boron tribromide; trichlorophosphate; In dichloromethane;
DOI:10.1002/1521-3765(20001117)6:22<4124::AID-CHEM4124>3.0.CO;2-M