2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine

Base Information

Chemical Name:2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine
CAS No.:32604-73-2
Molecular Formula:C₁₀H₁₃NO₃
Molecular Weight:195.218
Hs Code.:
Mol file:32604-73-2.mol

Synonyms:2-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-5-YLOXY)-ETHYLAMINE;5-(2-AMINOETHOXY)-2,3-DIHYDRO-1,4-BENZODIOXINE;

Suppliers and Price of 2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine

Chemical Property:

Vapor Pressure:0.000377mmHg at 25°C
PSA：53.71000
LogP:1.49560

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine

There total 6 articles about 2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 245762-30-5
2-(2,3-dihydrobenzo[1,4]dioxin-5-yloxy)ethyl azide

: 32604-73-2
2-(2,3-dihydrobenzo[1,4]dioxin-5-yloxy)-ethylamine

Guidance literature:: With water; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 18h;
DOI:10.1021/jm0304010

Reference yield:

: 10288-36-5
2,3-dihydro-1,4-benzodioxin-5-ol

: 32604-73-2
2-(2,3-dihydrobenzo[1,4]dioxin-5-yloxy)-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / Ph₃P; DIAD / tetrahydrofuran / 4 h

2: 72 percent / NaN₃ / dimethylformamide / 18 h / 60 °C

3: 62 percent / Ph₃P; H₂O / tetrahydrofuran / 18 h / 20 °C

With sodium azide; di-isopropyl azodicarboxylate; water; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; 1: Mitsunobu reaction;
DOI:10.1021/jm0304010

Reference yield:

: 1710-62-9
5-(2-bromoethoxy)-2,3-dihydrobenzo[b][1,4]dioxine

: 32604-73-2
2-(2,3-dihydrobenzo[1,4]dioxin-5-yloxy)-ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium iodide / dimethylformamide / 3 h / Heating

2: hydrazine hydrate / ethanol / 5 h / Heating

With hydrazine hydrate; potassium iodide; In ethanol; N,N-dimethyl-formamide; 1: Alkylation / 2: hydrazinolysis;
DOI:10.1016/S0968-0896(99)00265-5