4-Oxo-enoxacin

Base Information

Chemical Name:4-Oxo-enoxacin
CAS No.:87939-12-6
Molecular Formula:C₁₅H₁₅FN₄O₄
Molecular Weight:334.307
Hs Code.:
DSSTox Substance ID:DTXSID80236704
Nikkaji Number:J377.325F
Wikidata:Q83118712
ChEMBL ID:CHEMBL99850
Mol file:87939-12-6.mol

Synonyms:4-oxo-enoxacin;oxo-enoxacin;oxoenoxacin

Suppliers and Price of 4-Oxo-enoxacin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Oxo-enoxacin

Chemical Property:

Vapor Pressure:5.27E-19mmHg at 25°C
Boiling Point:672.5°C at 760 mmHg
Flash Point:360.5°C
PSA：108.02000
Density:1.471g/cm³
LogP:0.53080
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:334.10773313
Heavy Atom Count:24
Complexity:596

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNC(=O)C3)F)C(=O)O

Technology Process of 4-Oxo-enoxacin

There total 9 articles about 4-Oxo-enoxacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.4%

: 5625-67-2
2-Ketopiperazine

: 79286-73-0
1-ethyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-1,8-naphthyridine-3-carboxylic acid

: 87939-12-6
Oxoenoxacin

Guidance literature:: In acetonitrile; for 1h; Heating;
DOI:10.1021/jm00369a011

Reference yield:

: 87939-09-1
1-ethyl-6-fluoro-1,4-dihydro-7-hydroxy-4-oxo-1,8-naphthyridine-3-carboxylic acid

: 87939-12-6
Oxoenoxacin

Guidance literature:: Multi-step reaction with 2 steps

1: 91.4 percent / POCl₃ / 0.25 h / Heating

2: 71.4 percent / acetonitrile / 1 h / Heating

With trichlorophosphate; In acetonitrile;
DOI:10.1021/jm00369a011

Reference yield:

: 84233-60-3
ethyl 7-(4-acetyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate

: 87939-12-6
Oxoenoxacin

Guidance literature:: Multi-step reaction with 4 steps

1: 89.7 percent / K₂CO₃ / dimethylformamide / 3 h / 100 °C

2: 82 percent / 20percent NaOH / 43 h / Heating

3: 91.4 percent / POCl₃ / 0.25 h / Heating

4: 71.4 percent / acetonitrile / 1 h / Heating

With sodium hydroxide; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00369a011