3-(4-Methoxyphenyl)dihydrofuran-2,5-dione

Base Information

• Chemical Name: 3-(4-Methoxyphenyl)dihydrofuran-2,5-dione
• CAS No.: 32856-59-0
• Molecular Formula: C₁₁H₁₀O₄
• Molecular Weight: 206.198
• European Community (EC) Number: 832-955-1
• Nikkaji Number: J3.084.016J
• Mol file: 32856-59-0.mol

Synonyms:3-(4-methoxyphenyl)dihydrofuran-2,5-dione;32856-59-0;3-(4-methoxyphenyl)oxolane-2,5-dione;SCHEMBL11263779;GPNZEDFJEGABFE-UHFFFAOYSA-N;MFCD16306308;2-p-methoxyphenylbutanedioic anhydride;AKOS016361670;2-(p-methoxyphenyl)-succinic anhydride;NS-02208;EN300-704698;G55606;A913039;3-(4-Methoxy-phenyl)-dihydro-furan-2,5-dione, AldrichCPR

Chemical Property of 3-(4-Methoxyphenyl)dihydrofuran-2,5-dione

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 206.05790880
• Heavy Atom Count: 15
• Complexity: 266

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2CC(=O)OC2=O

Technology Process of 3-(4-Methoxyphenyl)dihydrofuran-2,5-dione

There total 7 articles about 3-(4-Methoxyphenyl)dihydrofuran-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2-(4-methoxyphenyl)succinic acid (13565-23-6,38971-62-9,117603-61-9,6331-59-5) → 3-(4-methoxyphenyl)dihydrofuran-2,5-dione (32856-59-0,67295-42-5)

Guidance literature:

With acetic anhydride; at 80 ℃; for 16h; Inert atmosphere;

DOI:10.1039/c2cc32147e

Reference yield:

→ 3-(4-methoxyphenyl)dihydrofuran-2,5-dione (32856-59-0,67295-42-5)

Guidance literature:

With acetyl chloride;

Reference yield:

→ 3-(4-methoxyphenyl)dihydrofuran-2,5-dione (32856-59-0,67295-42-5)

Guidance literature:

With thionyl chloride; acetyl chloride; (-)-<4-methoxy-phenyl>-succinic acid-anhydride;

DOI:10.1021/ja01866a053

upstream raw materials:

2-(4-methoxyphenyl)succinic acid

ethyl 2,3-dicyano-3-(4-methoxyphenyl)propanoate

diethyl-2-(4-methoxybenzylidene)malonate

4-methoxy-benzaldehyde

Downstream raw materials:

6β-[(Ξ)-3-carboxy-3-(4-methoxy-phenyl)-propionylamino]-penicillanic acid

3-<4-Brom-benzoyl>-3-<4-hydroxy-phenyl>-propionsaeure

3-<4-Iod-benzoyl>-2-<4-methoxy-phenyl>-propionsaeure

2-(4-methoxyphenyl)-4-oxo-4-phenylbutanoic acid